Korean J Med.
2003 Jul;65(1):104-110.
A case of systemic amyloidosis involving liver, kidney and peritoneum after cholecystectomy
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Inha University, Inchon, Korea. nhkimj@inha.ac.kr
- 2Department of Pathology, College of Medicine, Inha University, Inchon, Korea.
Abstract
- Amyloidosis is a heterogenous group of often fatal disorders characterized by extracellular deposition of a proteinaceous material with a unique fibrillar form in various tissues and organs. Deposition of amyloid may cause widespread dysfunction of the involved organs. Recently, we experienced a case of 40-year-old male patient with nephrotic syndrome, uncontrolled ascites and jaundice, which developed after cholecystectomy. We confirmed systemic amyloidosis involving kidney, liver and peritoneum by kidney and liver and peritoneum biopsy. The case that, having about a month of incubation period after cholecystectomy, amyloidosis occurred in a healthy man before the operation, and that amyloid was deposited in the peritoneum site incised during the operation provides grounds that amyloidosis may be triggered by cholecystectomy. Given the rarity of this case, the following is a report of this case and a review of the relevant literatures.
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