Clin Ultrasound.  2024 May;9(1):42-47. 10.18525/cu.2024.9.1.42.

Systemic Light Chain (Kappa Type) Amyloidosis Involving Liver and Bone Marrow, Heart, Lung

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
  • 2Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea
  • 3Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea

Abstract

Systemic amyloidosis is characterized by the accumulation of insoluble proteins in tissues including heart, kidney, liver and any other organs. Light chain amyloidosis is the most common type of primary amyloidosis. And it is generally considered to be the plasma cell dysfunction. Given its pathogenesis, it may affect any organ system. Thus, clinical presentation is variable and delayed diagnosis is common. Given these diagnostic difficulties, we presented a systemic amyloidosis presented as liver dysfunction.

Keyword

Amyloidosis; Liver disease; Immunoglobulin light-chain amyloidosis; Plasma cells; 아밀로이드증; 간질환; 아밀로이드경쇄 단백질; 형질세포
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