J Korean Epilepsy Soc.  2012 Dec;16(2):43-48.

Validity and Reliability of the Korean Version of the Liverpool Adverse Events Profile (K-LAEP) in People with Epilepsy

Affiliations
  • 1Department of Neurology, Kyungpook National University School of Medicine, Daegu, Korea. sppark@mail.knu.ac.kr

Abstract

PURPOSE
The aim of the study was to evaluate the validity and reliability of the Korean version of the Liverpool Adverse Events Profile (K-LAEP).
METHODS
An observational, cross-sectional study was performed in people with epilepsy (PWE) treated with a stable dose of antiepileptic drugs (AEDs). The scale was translated from the English version into a Korean version and was then back-translated to examine its accuracy. Patients completed the K-LAEP, Quality of Life in Epilepsy-31 (QOLIE-31), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI).
RESULTS
Three hundreds twelve patients were enrolled. The K-LAEP was completed in a short time, perceived as easy to comprehend, and there was no relevant information missing. Ceiling/floor effects were negligible. Internal consistency (Cronbach's alpha=0.9) and test-retest reliability (ICC=0.8) were satisfactory. The K-LAEP scores consistently correlated with QOLIE-31 (r= -0.528), BDI (r=0.526) and BAI (r=0.557) scores. When the K-LAEP was used to discriminate between patients with and without AED-related toxicity, the scores on the QOLIE, BDI and BAI corresponded. Anxiety symptoms were the strongest predictor to determine K-LAEP scores.
CONCLUSIONS
The K-LAEP scale reveals highly acceptable parameters of the validity and reliability, suggesting that it is an appropriate instrument to measure adverse effects among Korean PWE.

Keyword

Epilepsy; Antiepileptic drug; Adverse event; Validity; Reliability

MeSH Terms

Anticonvulsants
Anxiety
Cross-Sectional Studies
Depression
Epilepsy
Humans
Quality of Life
Reproducibility of Results
Anticonvulsants
Full Text Links
  • JKES
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr