Hanyang Med Rev.  2015 May;35(2):92-96. 10.7599/hmr.2015.35.2.92.

Sudden Sensorineural Hearing Loss

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea. logopas@korea.ac.kr

Abstract

Sudden sensorineural hearing loss (SSNHL) is defined as a sensorineural hearing loss of at least 30 dB in 3 consecutive speech frequencies that occurred within the previous 3 days. In most cases the cause is not identified, although various infective, vascular, and miscellaneous causes have been proposed. It has a reported incidence of 5 to 20 per 100,000 patients per year. Many treatments are used, including corticosteroids, antiviral drugs, hemodilution agents, minerals, vitamins, herbal preparations, batroxobin, carbogen, and oxygen-based treatments. Intra-tympanic dexamethasone injection into the middle ear may be useful to SSNHL patients with profound hearing loss that is intractable to medical treatment or who also have diabetes mellitus. In SSNHL, early treatment with combined modalities that include steroid injection is generally recognized as the current best practice. The spontaneous recovery rates have been reported to be between 32-70%, and although various treatment protocols have been tried, only about half of patients completely recover, usually within 2 weeks. There is much to learn about pathogenesis of sudden sensorineural hearing loss, and more clinical trials are needed to establish evidence-based management.

Keyword

Hearing Loss, Sudden; Hearing Loss, Sensorineural; Steroids; Dexamethasone; Antiviral Agents

MeSH Terms

Adrenal Cortex Hormones
Antiviral Agents
Batroxobin
Clinical Protocols
Dexamethasone
Diabetes Mellitus
Ear, Middle
Hearing Loss
Hearing Loss, Sensorineural*
Hearing Loss, Sudden
Hemodilution
Humans
Incidence
Minerals
Plant Preparations
Practice Guidelines as Topic
Steroids
Vitamins
Adrenal Cortex Hormones
Antiviral Agents
Batroxobin
Dexamethasone
Minerals
Plant Preparations
Steroids
Vitamins

Cited by  3 articles

Etiology and Rehabilitation of Sensorineural Hearing Loss
Seung Hwan Lee
Hanyang Med Rev. 2015;35(2):55-56.    doi: 10.7599/hmr.2015.35.2.55.

A Comparative Study on the Treatment Effect of Lipo-Prostagladin with Hypertension and Diabetes Mellitus in Sudden Sensorineural Hearing Loss Patients
Hye-Jeong Heo, Chul-Hee Choi, Myung Gu Kim, Sung Hwa Hong, Ji Won Seo
Korean J Otorhinolaryngol-Head Neck Surg. 2021;64(8):540-547.    doi: 10.3342/kjorl-hns.2020.01053.

A Case of Bilateral Sequential Sudden Sensorineural Hearing Loss in Protein S Deficiency and Successful Recovery of Hearing After Cochlear Implantation
Dabin Lee, Euyhyun Park, Hak Hyun Jung, Gi Jung Im
Korean J Otorhinolaryngol-Head Neck Surg. 2023;66(10):686-691.    doi: 10.3342/kjorl-hns.2023.00514.


Reference

1. Schreiber BE, Agrup C, Haskard DO, Luxon LM. Sudden sensorineural hearing loss. Lancet. 2010; 375:1203–1211.
Article
2. Chau JK, Lin JR, Atashband S, Irvine RA, Westerberg BD. Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope. 2010; 120:1011–1021.
Article
3. Nosrati-Zarenoe R, Arlinger S, Hultcrantz E. Idiopathic sudden sensorineural hearing loss: results drawn from the Swedish national database. Acta Otolaryngol. 2007; 127:1168–1175.
Article
4. Alexander TH, Harris JP. Incidence of sudden sensorineural hearing loss. Otol Neurotol. 2013; 34:1586–1589.
Article
5. Stokroos RJ, Albers FW. The etiology of idiopathic sudden sensorineural hearing loss. A review of the literature. Acta Otorhinolaryngol Belg. 1996; 50:69–76.
6. Fukuda S, Chida E, Kuroda T, Kashiwamura M, Inuyama Y. An anti-mumps IgM antibody level in the serum of idiopathic sudden sensorineural hearing loss. Auris Nasus Larynx. 2001; 28:Suppl. S3–S5.
Article
7. Xenellis J, Nikolopoulos TP, Stavroulaki P, Marangoudakis P, Androulakis M, Tsangaroulakis M, et al. Simultaneous and sequential bilateral sudden sensorineural hearing loss: are they different from unilateral sudden sensorineural hearing loss. ORL J Otorhinolaryngol Relat Spec. 2007; 69:306–310.
Article
8. Hendrix RA, DeDio RM, Sclafani AP. The use of diagnostic testing in asymmetric sensorineural hearing loss. Otolaryngol Head Neck Surg. 1990; 103:593–598.
Article
9. Aarnisalo AA, Suoranta H, Ylikoski J. Magnetic resonance imaging findings in the auditory pathway of patients with sudden deafness. Otol Neurotol. 2004; 25:245–249.
Article
10. Cadoni G, Cianfoni A, Agostino S, Scipione S, Tartaglione T, Galli J, et al. Magnetic resonance imaging findings in sudden sensorineural hearing loss. J Otolaryngol. 2006; 35:310–316.
Article
11. Koc A, Sanisoglu O. Sudden sensorineural hearing loss: literature survey on recent studies. J Otolaryngol. 2003; 32:308–313.
Article
12. Wilson WR, Byl FM, Laird N. The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol. 1980; 106:772–776.
Article
13. Wei BP, Stathopoulos D, O'Leary S. Steroids for idiopathic sudden sensorineural hearing loss. Cochrane Database Syst Rev. 2013; 7:Cd003998.
Article
14. Conlin AE, Parnes LS. Treatment of sudden sensorineural hearing loss: II. A Meta-analysis. Arch Otolaryngol Head Neck Surg. 2007; 133:582–586.
15. Free RH, Smale ND, de Kleine E, van der Laan BF. Side effects of oral dexamethasone pulse therapy for idiopathic sudden sensorineural hearing loss. Otol Neurotol. 2009; 30:691.
Article
16. Parnes LS, Sun AH, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope. 1999; 109:1–17.
Article
17. Rauch SD, Halpin CF, Antonelli PJ, Babu S, Carey JP, Gantz BJ, et al. Oral vs intratympanic corticosteroid therapy for idiopathic sudden sensorineural hearing loss: a randomized trial. JAMA. 2011; 305:2071–2079.
Article
18. Kim SH, Jung SY, Kim MG, Byun JY, Park MS, Yeo SG. Comparison of Steroid Administration Methods in Patients with Idiopathic Sudden Sensorineural Hearing Loss: a retrospective observational study. Clin Otolaryngol. Forthcoming 2014.
Article
19. Choung YH, Park K, Shin YR, Cho MJ. Intratympanic dexamethasone injection for refractory sudden sensorineural hearing loss. Laryngoscope. 2006; 116:747–752.
Article
20. Wiles NM, Hunt BJ, Callanan V, Chevretton EB. Sudden sensorineural hearing loss and antiphospholipid syndrome. Haematologica. 2006; 91:Ecr46.
21. Yoon TH, Paparella MM, Schachern PA, Alleva M. Histopathology of sudden hearing loss. Laryngoscope. 1990; 100:707–715.
Article
22. Jun HJ, Chang J, Im GJ, Kwon SY, Jung H, Choi J. Analysis of frequency loss as a prognostic factor in idiopathic sensorineural hearing loss. Acta Otolaryngol. 2012; 132:590–596.
Article
23. Ohashi T, Nishino H, Arai Y, Nishimoto Y, Koizuka I. Prognostic evaluation of electrocochleography in idiopathic sudden sensorineural hearing loss. Acta Otolaryngol. 2012; 132:133–140.
Article
24. Trautwein P, Hofstetter P, Wang J, Salvi R, Nostrant A. Selective inner hair cell loss does not alter distortion product otoacoustic emissions. Hear Res. 1996; 96:71–82.
Article
25. Korres S, Stamatiou GA, Gkoritsa E, Riga M, Xenelis J. Prognosis of patients with idiopathic sudden hearing loss: role of vestibular assessment. J Laryngol Otol. 2011; 125:251–257.
Article
26. Ryu OH, Choi MG, Park CH, Kim DK, Lee JS, Lee JH. Hyperglycemia as a potential prognostic factor of idiopathic sudden sensorineural hearing loss. Otolaryngol Head Neck Surg. 2014; 150:853–858.
Article
Full Text Links
  • HMR
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr