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Pharmacological treatment of the patients with croup

Jang YY, Chung HL

Background: Croup is a respiratory illness usually caused by acute viral infection of the larynx, trachea, and bronchi, and characterized by the abrupt onset of a barking cough, inspiratory stridor,...
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The Effect of the Timing of Dexamethasone Administration in Patients with COVID-19 Pneumonia

Lee HW, Park J, Lee JK, Park TY, Heo EY

Background: Despite the proven benefits of dexamethasone in hospitalized coronavirus disease 2019 (COVID-19) patients, the optimum time for the administration of dexamethasone is unknown. We investigated the progression of COVID-19...
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Surgical Management of Complications after Dexamethasone Implant Injection

Kim SH, Choi Y, Choi SK, Lee JJ, Byon IS, Lee JE, Park SW

Purpose: To report complications requiring surgical management related to intravitreal dexamethasone implant. Methods: The medical records of patients who received intravitreal dexamethasone implant injection from June 2013 to March 2020 were...
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Comparison of prophylactic effect of topical Alchemilla vulgaris in glycerine versus that of dexamethasone on postoperative sore throat after tracheal intubation using a double-lumen endobronchial tube: a randomized controlled study

Chung CJ, Jeong SY, Jeong JH, Kim SW, Lee KH, Kim JH, Park SY, Choi SR

Background: Sore throat and hoarseness frequently occur following general anesthesia with tracheal intubation and are effectively reduced when dexamethasone is used prophylactically. Alchemilla vulgaris in glycerine (Neo Mucosal Activator®) suppresses...
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The Effect of an Intravitreal Dexamethasone Implant for Refractory Posterior Scleritis

Choi SK, Choi YA, Kim SH, Lee JJ, Byon IS, Lee JE, Park SW

Purpose: To report the effect of an intravitreal dexamethasone implant on refractory posterior scleritis. Methods: The medical records of patients treated with an intravitreal dexamethasone implant for non-infectious refractory posterior scleritis...
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Suppression of Fibrotic Reactions of Chitosan-Alginate Microcapsules Containing Porcine Islets by Dexamethasone Surface Coating

Kim MJ, Park HS, Kim JW, Lee EY, Rhee M, You YH, Khang G, Park CG, Yoon KH

Background: The microencapsulation is an ideal solution to overcome immune rejection without immunosuppressive treatment. Poor biocompatibility and small molecular antigens secreted from encapsulated islets induce fibrosis infiltration. Therefore, the aims...
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Comparative efficiency of the preoperative pterygomandibular space injection of two doses of dexamethasone in mandibular third molar surgery

Wanithanont P, Chaiyasamut T, Vongsavan K, Bhattarai BP, Pairuchvej V, Kiattavorncharoen S, Wongsirichat N

Background: Impacted mandibular third molar removal is one of the most commonly performed oral surgical procedures. This procedure can lead to several postoperative complications, such as trismus, facial swelling, and...
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Systemic Immunomodulatory Effects of Combinatorial Treatment of Thalidomide and Dexamethasone on T Cells and Other Immune Cells

Kim EJ, Kim JY, Choi HY, Lee H, Lee J, Kim MS, Kim YS, Huh KH, Kim BS

Purpose In organ transplantation, the need for immune modulation rather than immune suppression has been emphasized. In this study, we investigated whether combinatorial treatments of with thalidomide (TM) and dexamethasone (DX)...
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Delayed Symptoms after Intralenticular Dexamethasone Implant

Jo YC, Yeom MI, Kim SS

Purpose: To report a case of delayed symptoms after intralenticular dexamethasone implant (Ozurdex ® ; Allergan, Irvine, CA, USA). Case summary: A 65-year-old male was referred for myodesopsia and decreased visual...
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Dexamethasone Interferes with Autophagy and Affects Cell Survival in Irradiated Malignant Glioma Cells

Komakech A, Im JH, Gwak HS, Lee KY, Kim JH, Yoo BC, Cheong H, Park JB, Kwon JW, Shin SH, Yoo H

Objective : Radiation is known to induce autophagy in malignant glioma cells whether it is cytocidal or cytoprotective. Dexamethasone is frequently used to reduce tumor-associated brain edema, especially during radiation therapy....
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Factors Associated with Clinical Response to Low-Dose Dexamethasone Therapy for Bronchopulmonary Dysplasia in Very Low Birth Weight Infants

Shin J, Kim SH, Jung YH, Choi CW, Kim BI

Purpose: To identify factors associated with the clinical response to low-dose dexamethasone therapy (LDDT) in preterm infants for bronchopulmonary dysplasia (BPD). Methods: We used a retrospective medical record review to evaluate...
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Comparing pain relief and functional improvement between methylprednisolone and dexamethasone lumbosacral transforaminal epidural steroid injections: a self-controlled study

Donohue NK, Tarima SS, Durand MJ, Wu H

Background: Previous studies have shown varying results between lumbosacral transforaminal epidural steroid injections (TFESIs) performed with particulate versus non-particulate corticosteroids. The purpose of this study was to investigate the difference...
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Questionnaire survey on the management of pregnant women with preterm premature rupture of membranes

Kim SY, Kwon HS, Lee J, Sul AR, Ko HS, Yang JI

Objective The aim of this survey was to study the status of the actual practice in the management of preterm premature rupture of membranes (PPROM) between 34.0 and 36.6 weeks of gestation. Methods This...
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Objective Verification of Acute Tinnitus and Validation of Efficacy of Systemic Steroids in Rats

Kim YC, Kim H, Kim YS, Jung SK, Park IY, Choung YH, Jang JH

Background This study was performed to identify acute tinnitus and evaluate the efficacy of steroids for noise-induced acute tinnitus by measuring the gap-prepulse inhibition of the acoustic startle (GPIAS) value in...
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Clinical Outcomes of Cervical Transforaminal Epidural Block Using Local Anesthetics with or without a Steroid for Cervical Spondylotic Radiculopathy

Park EJ, Kim SM, Chung S, Min WK

Objectives: To evaluate and compare the clinical outcomes of cervical transforaminal epidural block (CTEB) using local anesthetics with or without a steroid for cervical spondylotic radiculopathy (CSR). Summary of Literature Review:...
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Persistent Hiccups after Cervical Selective Nerve Root Block

Kim NE, Heo GA, Kim BG, Park KH, Uhm JW

Persistent hiccups are rare complications following epidural steroid injections. Although the underlying etiology is not clearly understood, corticosteroids are the drug group referenced most frequently in the literature as being...
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Short-term Results of Intravitreal Dexamethasone Implant Combined with Bevacizumab versus Intravitreal Bevacizumab for Treatment-naive Diabetic Macular Edema

Lee YJ, Kang KD

Purpose: To compare the visual and anatomical outcomes of intravitreal bevacizumab combined with the dexamethasone intravitreal implant (Ozurdex®) and bevacizumab monotherapy in eyes with treatment-naive diabetic macular edema. Methods: We retrospectively...
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Comparison among Three Different Steroid Therapies for Idiopathic Sudden Sensorineural Hearing Loss

Jung DJ, Lee J, Yoo MH, Lee KY

Background and Objectives The optimal dose or type of systemic steroid for treating idiopathic sudden sensorineural hearing loss (ISSNHL) is unclear. Herein, we compare the efficacy of three steroid treatment...
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Two-dimensional Quantitative Effects of Anti-vascular Endothelial Growth Factor and Dexamethasone Implants on Retinal Vein Occlusion

Jang M, Lee H, Kim HC, Chung H

Purpose: We quantitatively analyzed the therapeutic effects of intravitreal anti-vascular endothelial growth factor (anti-VEGF) and dexamethasone implants used to treat macular edema caused by retinal vein occlusion. Methods: Eighty-three patients with...
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Effect of dexamethasone gargle, intravenous dexamethasone, and their combination on postoperative sore throat: a randomized controlled trial

Ki S, Myoung I, Cheong S, Lim S, Cho K, Kim Mh, Han Y, Oh M, Park Y, Kim K, Lee J

Background: Postoperative sore throat (POST) is a complication that decreases patient satisfaction and increases postoperative complaints. The present study was conducted to investigate effects of gargling with dexamethasone, intravenous dexamethasone...
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