J Korean Med Sci.  2013 Sep;28(9):1334-1339. 10.3346/jkms.2013.28.9.1334.

Sleep Duration and Glycemic Control in Patients with Diabetes Mellitus: Korea National Health and Nutrition Examination Survey 2007-2010

• Kim BK
• Kim BS
• An SY
• Lee MS
• Choi YJ
• Han SJ
• Chung YS
• Lee KW
• Kim DJ

• KMID: 1793049
• DOI: http://doi.org/10.3346/jkms.2013.28.9.1334

Abstract

Short sleep duration has been reported to increase the risk of diabetes. However, the influence of sleep duration on glycemic control in diabetic patients has not been clarified. In this study we evaluated the association between sleep duration and glycemic control in diabetic patients. We analyzed the data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2007-2010. Sleep duration was classified into five groups: <6, 6, 7, 8, and > or =9 h/day. Fasting blood glucose and HbA1c showed a U-shaped trend according to sleep duration. Sleep duration of 7 h/day had the lowest HbA1c (7.26%) among the subjects (P=0.026). In the older age group (> or =65 yr), a sleep duration of 6 h/day was associated with the lowest HbA1c (7.26%). The adjusted odds ratio (OR) with a 95% confidence interval (CI) of worse glycemic control (HbA1c > or =7.0%) in group of sleep duration of > or =9 h/day was 1.48 (1.04-2.13) compared with the group of 7 h/day. This relationship disappeared after adjusting duration of diabetes (OR, 1.38; 95% CI, 0.93-2.03). Our results suggest that sleep duration and glycemic control in diabetic patients has U-shaped relationship which was mainly affected by duration of diabetes.

Keyword

Sleep; Diabetes Mellitus; Insulin Resistance

MeSH Terms

Age Factors
Aged
Asian Continental Ancestry Group
Blood Glucose/*analysis
Diabetes Mellitus, Type 2/*diagnosis/metabolism
Female
Hemoglobin A, Glycosylated/*analysis
Humans
Insulin Resistance
Male
Middle Aged
Nutrition Surveys
Odds Ratio
Republic of Korea
Risk Factors
Sleep/*physiology
Blood Glucose
Hemoglobin A, Glycosylated

Figure

• 

  Fig. 1 Glycemic levels according to sleep duration by sex and age. (A) Fasting blood glucose levels according to sleep duration by sex. (B) Fasting blood glucose levels according to sleep duration by age. (C) HbA1c levels according to sleep duration by sex. (D) HbA1c levels according to sleep duration by age.

• 

  Fig. 2 Insulin resistance levels according to sleep duration.

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