Korean J Parasitol.  2012 Dec;50(4):349-352.

Intestinal Paragonimiasis with Colonic Ulcer and Hematochezia in An Elderly Taiwanese Woman

Affiliations
  • 1Division of Nephrology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, 250 Wu-Xing Street, Taipei 11031, Taiwan.
  • 2Department of Parasitology, College of Medicine, Taipei Medical University, 250 Wu-Xing Street, College of Medicine, Taipei 11031, Taiwan. tedfan@tmu.edu.tw
  • 3Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA.
  • 4Center for International Tropical Medicine, College of Medicine, Taipei Medical University, 250 Wu-Xing Street, Taipei 11031, Taiwan.

Abstract

A 94-year-old female with end-stage renal disease presents with fever, fatigue, and hematochezia. She had previously resided in Hunan Province, China, and Myanmar, and she immigrated to Taiwan 30 years ago. Colonoscopy revealed a colonic ulcer. Biopsy of the colonic ulcer showed ulceration of the colonic mucosa, and many Paragonimus westermani-like eggs were noted. Serum IgG antibody levels showed strong reactivity with P. westermani excretory-secretory antigens by ELISA. Intestinal paragonimiasis was thus diagnosed according to the morphology of the eggs and serologic finding. After treatment with praziquantel, hematochezia resolved. The present case illustrates the extreme manifestations encountered in severe intestinal paragonimiasis.

Keyword

Paragonimus westermani; ectopic; colonic ulcer; hematochezia; praziquantel

MeSH Terms

Aged, 80 and over
Animals
Anthelmintics/therapeutic use
Antibodies, Helminth/blood
Antigens, Helminth/immunology
Colonic Diseases/complications/drug therapy/*pathology
Colonoscopy
Enzyme-Linked Immunosorbent Assay
Female
Gastrointestinal Hemorrhage/complications/drug therapy/*pathology
Humans
Intestinal Diseases, Parasitic/complications/drug therapy/parasitology/*pathology
Kidney Failure, Chronic/complications
Paragonimiasis/complications/drug therapy/parasitology/*pathology
Paragonimus westermani/*immunology
Praziquantel/therapeutic use
Taiwan
Ulcer/complications/drug therapy/*pathology
Anthelmintics
Antibodies, Helminth
Antigens, Helminth
Praziquantel
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