Korean J Intern Med.  2010 Mar;25(1):51-57. 10.3904/kjim.2010.25.1.51.

Prevalence of Depression and Anxiety in Outpatients with Chronic Airway Lung Disease

• Ryu YJ
• Chun EM
• Lee JH
• Chang JH

• KMID: 1785654
• DOI: http://doi.org/10.3904/kjim.2010.25.1.51

Abstract

BACKGROUND/AIMS
Patients with chronic airway lung diseases often experience depression and anxiety, but little information is available regarding Koreans with these conditions. We thus assessed depression and anxiety in Korean patients with chronic airway lung diseases.
METHODS
The degree of depression and anxiety in 84 outpatients with chronic obstructive pulmonary disease (COPD), 37 with asthma, 33 with bronchiectasis, and 73 healthy controls were evaluated by the Beck Depression Inventory (BDI) and the State-Trait Anxiety Inventory (STAI).
RESULTS
The patients with COPD and bronchiectasis had higher BDI scores and were more likely than controls to experience depression ([COPD, 17; range, 0 to 42; prevalence, 55%], [bronchiectasis, 16; range, 3 to 51; prevalence, 55%], [controls, 13; range, 0 to 31; prevalence, 30%], p < 0.05). The state-anxiety scores of the patients were higher than those of the controls, but only the bronchiectasis group demonstrated a higher frequency of state-anxiety compared with the controls (39 vs. 16%, patients vs. controls, p = 0.015). Among all patients, 22% presented with concomitant depression and state-anxiety, and 25% demonstrated depression and trait-anxiety. Depression was positively correlated with both state-anxiety (r = 0.644) and trait-anxiety (r = 0.597, p < 0.0001). Irrespective of individual diagnosis, post-bronchodilator FEV1 (odds ratio [OR], 0.972; p = 0.027) and smoking history (OR, 3.894; p = 0.018) were independent risk factors for depression in patients with chronic airway lung diseases.
CONCLUSIONS
Chronic airway lung diseases are associated with depression and/or anxiety, particularly in those with a higher airflow limitation and/or history of smoking.

Keyword

Depression; Anxiety; Pulmonary disease, chronic obstructive; Asthma; Bronchiectasis

MeSH Terms

Aged
Aged, 80 and over
Anxiety/*epidemiology
Asthma/epidemiology/psychology
Bronchiectasis/epidemiology/psychology
Chronic Disease
Depression/*epidemiology
Female
Humans
Male
Middle Aged
Prevalence
Pulmonary Disease, Chronic Obstructive/*epidemiology/*psychology
Risk Factors
Smoking/epidemiology/psychology