Korean J Intern Med.  2006 Jun;21(2):116-119. 10.3904/kjim.2006.21.2.116.

Concurrence of Sjogren's Syndrome in a Patient with Chlamydia-induced Reactive Arthritis: An Unusual Finding

• Chang HK
• Bang KT
• Lee BH
• Kim JH
• Bae KW
• Kim MJ
• Kim SK

• KMID: 1785608
• DOI: http://doi.org/10.3904/kjim.2006.21.2.116

Abstract

A 40-year-old Korean man presented with painful swelling and tenderness of both ankle joints as well as the plantar surfaces of both feet, along with inflammatory back pain, and a purulent discharge from the urethral orifice. The patient also complained of sicca-like symptoms including dry eyes and dry mouth. An immunological analysis revealed a high titer of rheumatoid factor, positive results for antinuclear antibody and anti-Ro antibody, and a positive result for HLA-B27. An antibody titer for Chlamydia was also significantly increased. Positive results of the Schirmer's test and for keratoconjunctivitis sicca were confirmed by an ophthalmologist. These clinical manifestations were compatible with Chlamydia-induced reactive arthritis (ReA) accompanied by Sjogren's syndrome (SS). This is the first report of the combination of these two distinct disease entities in the Korean population.

Keyword

Reactive arthritis; Sjogren's syndrome

MeSH Terms

Sjogren's Syndrome/*complications
Male
Humans
*Chlamydia trachomatis
Chlamydia Infections/*complications
Arthritis, Reactive/*complications
Antibodies, Antinuclear/blood
Adult