Korean J Otorhinolaryngol-Head Neck Surg.  2015 Feb;58(2):130-133. 10.3342/kjorl-hns.2015.58.2.130.

A Case of Systemic Lupus Erythematosus Involved Central Nervous System Presenting as Acute Sialoadenitis

• Kim DH
• Kim HB
• Kim DR
• Cho JH

• KMID: 1784964
• DOI: http://doi.org/10.3342/kjorl-hns.2015.58.2.130

Abstract

Systemic lupus erythematosus (SLE) is a multi organ-involving systemic disease and usually manifests as musculoskeletal and cutaneous presentation. Acute sialoadenitis in lupus patients is not a typical manifestation. We report the case of a 23-year-old woman who presented with both parotid and submandibular gland painful swelling with highly elevated level of serum amylase. Epileptic seizure unexpectedly occurred during conservative treatment of the mentioned disease. After a close examination for the systemic or underlying disease, SLE was detected by specific autoantibody. The patient was uneventfully discharged after steroid pulse therapy. Although it is a very rare manifestation, autoimmune disease such as SLE should be included in differential diagnosis, especially in young women, when acute sialoadenitis is not improved with conservative management.

Keyword

Seizure; Sialoadenitis; Systemic lupus erythematosus

MeSH Terms

Amylases
Autoimmune Diseases
Central Nervous System*
Diagnosis, Differential
Epilepsy
Female
Humans
Lupus Erythematosus, Systemic*
Seizures
Sialadenitis*
Submandibular Gland
Young Adult
Amylases