Yonsei Med J.  2009 Feb;50(1):55-59. 10.3349/ymj.2009.50.1.55.

The Efficacy of Postoperative Prophylactic Antibiotics in Orthognathic Surgery: A Prospective Study in Le Fort I Osteotomy and Bilateral Intraoral Vertical Ramus Osteotomy

• Kang SH
• Yoo JH
• Yi CK

• KMID: 1782968
• DOI: http://doi.org/10.3349/ymj.2009.50.1.55

Abstract

PURPOSE
This study examined the efficacy of the postoperative prophylactic antibiotics used in orthognathic surgery. The prevalence of surgical site infections (SSIs) was determined according to the use of postoperative prophylactic antibiotics.
PATIENTS AND METHODS
Fifty-six patients were divided into 2 groups. Each patient intravenously received 1.0 g of a third-generation cephalosporin (Cefpiramide) 30 minutes before surgery. Among them, 28 patients in the control group received 1.0 g Cefpiramide twice daily until the third day after surgery. The postoperative wounds were examined regularly for the presence of infectious signs.
RESULTS
There was no significant difference in the incidence of postoperative wound infections between patients who had received postoperative prophylactic antibiotic administration and those who had not (p = 0.639).
CONCLUSION
Prolonged prophylactic antibiotic use after orthognathic surgery may not be necessary, provided that there are no other significant factors for wound infections.

Keyword

Orthognathic surgery; prophylactic antibiotics; surgical site infection

MeSH Terms

Adult
Anti-Bacterial Agents/*administration & dosage
Cephalosporins/*administration & dosage
Female
Humans
Injections, Intravenous
Male
Mandible/surgery
Maxilla/surgery
*Oral Surgical Procedures
*Osteotomy, Le Fort
Prevalence
Prospective Studies
Surgical Wound Infection/*drug therapy/epidemiology/*prevention & control
Young Adult

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