Infect Chemother.  2012 Feb;44(1):11-16. 10.3947/ic.2012.44.1.11.

Comparison of the Incidence and Clinical Characteristics of Gram-positive and Gram-negative Surgical Site Infections after Gastric Surgery

Affiliations
  • 1Department of Internal Medicine, Yonsei University Collegeof Medicine, Severance Hospital, Seoul, Korea. jmkim@yuhs.ac
  • 2Department of Internal Medicine, University College of Medicine, Anam Hospital, Seoul, Korea.
  • 3Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea.
  • 4Department of Internal Medicine, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Korea.
  • 5Department of Internal Medicine, Gachon University School of medicine, Gil Medical Center, Incheon, Korea.
  • 6Department of Internal Medicine, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Korea.
  • 7Department of Internal Medicine, Ewha Womans University School of Medicine, Mok-Dong Hospital, Seoul, Korea.
  • 8Department of Internal Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.
  • 9Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, Wonju, Korea.
  • 10Department of Internal Medicine, Hallym University College of Medicine, Sacred Heart Hospital, Anyang, Korea.
  • 11Department of Internal Medicine, Korea University College of Medicine, Ansan Hospital, Ansan, Korea.
  • 12Department of Internal Medicine, Konyang University College of Medicine, Konyang University Hospital, Daejeon, Korea.
  • 13Department of Internal Medicine, Hanil General Hospital, Seoul, Korea.

Abstract

BACKGROUND
Surgical site infection (SSI) is prominent among the total incidence of healthcare-associated infections, and is a major contributing factor in the trend of increasing medical costs. There have been numerous efforts to analyze the conditions and causes of SSI for the purpose of prevention. In this study of SSI development after gastric surgery, we evaluated the prevalence of specific pathogens and compared the clinical characteristics observed between gram-positive (GPB) and gram-negative bacteria (GNB).
MATERIALS AND METHODS
We conducted a retrospective study of patients who developed SSI within 30 days after gastric surgery at 13 clinics in Korea, between January 2007 and December 2008. Only those cases of SSI which included confirmed pathogen were included in this study.
RESULTS
Among the 121 patients who developed SSI, GPB were observed in 32 patients and 36 cases, and GNB were isolated in 32 patients and 36 cases. Methicillin resistant Staphylococcus aureus (MRSA) was the most frequently isolated pathogen in this analysis. There were no differences observed between the GPB and GNB group in terms of baseline characteristics, patient or procedure related risk factors, or factors associated with prophylactic antibiotics.
CONCLUSIONS
In the previous studies of the occurrence of SSI after gastric surgery, it was reported that the majority of observed pathogens were enteric GNB. Further studies of the incidence of SSI after gastric surgery, particularly those related to MRSA infection, are necessary.

Keyword

Surgical site infection; Gastric surgery; Pathogens; Gram-positive bacteria; Gram-negative bacteria

MeSH Terms

Gram-Negative Bacteria
Gram-Positive Bacteria
Humans
Incidence
Korea
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus
Prevalence
Retrospective Studies
Risk Factors
Staphylococcus aureus

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