Korean J Hepatol.
2010 Mar;16(1):75-78. 10.3350/kjhep.2010.16.1.75.
A case report of alverine-citrate-induced acute hepatitis
- Affiliations
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- 1Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea. jin@inha.ac.kr
- 2Department of Pathology, Inha University School of Medicine, Incheon, Korea.
- KMID: 1782223
- DOI: http://doi.org/10.3350/kjhep.2010.16.1.75
Abstract
- Alverine citrate is one of the most commonly used antispasmodic drugs for patients with irritable bowel syndrome. Alverine-citrate-induced hepatotoxicity is extremely rare, with only a few cases having been reported worldwide. We present a case of a 75-year-old female patient who experienced complicated jaundice and abdominal discomfort after taking alverine citrate. Other causes of hepatitis were ruled out and the results of the liver function test returned to normal after ceasing the drug. This is the first case report in Korea of alverine-citrate-induced hepatotoxicity.
MeSH Terms
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Acute Disease
Aged
Citrates/*adverse effects/therapeutic use
Drug-Induced Liver Injury/*diagnosis/etiology/pathology
Female
Humans
Irritable Bowel Syndrome/drug therapy
Liver Function Tests
Parasympatholytics/*adverse effects/therapeutic use
Propylamines/*adverse effects/therapeutic use
Tomography, X-Ray Computed
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