Korean J Pain.  2012 Apr;25(2):105-107. 10.3344/kjp.2012.25.2.105.

Treatment of Idiopathic Persistent Hiccups with Positive Pressure Ventilation: A Case Report

• Byun SH
• Jeon YH

• KMID: 1778994
• DOI: http://doi.org/10.3344/kjp.2012.25.2.105

Abstract

A 41-year-old male patient presented with idiopathic persistent hiccups. The hiccups did not respond to pharmacologic treatments including cisapride, omeprazole, and baclofen. Phrenic nerve block was also ineffective. However, the persistent hiccups were successfully treated with short-term positive pressure ventilation using a short-acting muscle relaxant.

Keyword

hiccups; positive pressure ventilation

MeSH Terms

Adult
Baclofen
Cisapride
Hiccup
Humans
Male
Muscles
Omeprazole
Phrenic Nerve
Positive-Pressure Respiration
Baclofen
Cisapride
Omeprazole

Reference

1. Friedman NL. Hiccups: a treatment review. Pharmacotherapy. 1996; 16:986–995. PMID: 8947969.

2. Rousseau P. Hiccups. South Med J. 1995; 88:175–181. PMID: 7839159.

3. Launois S, Bizec JL, Whitelaw WA, Cabane J, Derenne JP. Hiccup in adults: an overview. Eur Respir J. 1993; 6:563–575. PMID: 8491309.

4. Okuda Y, Kamishima K, Arai T, Asai T. Combined use of ultrasound and nerve stimulation for phrenic nerve block. Can J Anaesth. 2008; 55:195–196. PMID: 18310638.

5. Lewis JH. Hiccups: causes and cures. J Clin Gastroenterol. 1985; 7:539–552. PMID: 2868032.

6. Petroianu G, Hein G, Petroianu A, Bergler W, Rüfer R. Idiopathic chronic hiccup: combination therapy with cisapride, omeprazole, and baclofen. Clin Ther. 1997; 19:1031–1038. PMID: 9385490.

7. Guelaud C, Similowski T, Bizec JL, Cabane J, Whitelaw WA, Derenne JP. Baclofen therapy for chronic hiccup. Eur Respir J. 1995; 8:235–237. PMID: 7758557.

8. Petroianu G. Idiopathic chronic hiccup (ICH): phrenic nerve block is not the way to go. Anesthesiology. 1998; 89:1284–1285. PMID: 9822029.

9. Moore DC. Regional block: a handbook for use in the clinical practice of medicine and surgery. 1981. 4th ed. Springfiled, IL: Charles C Thomas Publisher Ltd;p. 138–142.

10. Saitto C, Gristina G, Cosmi EV. Treatment of hiccups by continuous positive airway pressure (CPAP) in anesthetized subjects. Anesthesiology. 1982; 57:345. PMID: 6751158.

11. Lierz P, Felleiter P. Anesthesia as therapy for persistent hiccups. Anesth Analg. 2002; 95:494–495. PMID: 12145080.

12. Oshima T, Dohi S. Isoflurane facilitates hiccup-like reflex through gamma aminobutyric acid (GABA)A- and suppresses through GABAB-receptors in pentobarbital-anesthetized cats. Anesth Analg. 2004; 98:346–352. PMID: 14742368.