J Korean Med Sci.  2007 Jun;22(3):513-517. 10.3346/jkms.2007.22.3.513.

Obesity and the Metabolic Syndrome in Korean Adolescents

• Ryu SY
• Kweon SS
• Park HC
• Shin JH
• Rhee JA

• KMID: 1778363
• DOI: http://doi.org/10.3346/jkms.2007.22.3.513

Abstract

This study evaluated the prevalence of metabolic syndrome and investigated its association with being overweight in Korean adolescents. Data were obtained from 1,393 students between 12 and 13 yr of age in a cross-sectional survey. We defined the metabolic syndrome using criteria analogous to the Third Report of the Adult Treatment Panel (ATP III) as having at least three of the following: fasting triglycerides > or =100 mg/dL; HDL <50 mg/dL; fasting glucose > or =110 mg/dL; waist circumference >75th percentile for age and gender; and systolic blood pressure >90th percentile for age, gender, and height. Weight status was assessed using the age- and gender-specific body mass index (BMI), and a BMI > or =85th percentile was classified as overweight. Of the adolescents, 5.5% met the criteria for the metabolic syndrome, and the prevalence increased with weight status; it was 1.6% for normal weight and 22.3% in overweight (p<0.001). In multivariate logistic regression analyses among adolescents, overweight status was independently associated with the metabolic syndrome (odds ratio, 17.7; 95% confidence interval, 10.0-31.2). Since childhood metabolic syndrome and obesity likely persist into adulthood, early identification helps target interventions to improve future cardiovascular health.

Keyword

Metabolic Syndrome; Overweight; Adolescents

MeSH Terms

Adolescent
Blood Pressure
Body Mass Index
Body Weight
Cardiovascular Diseases/complications/etiology
Female
Humans
Korea
Male
Metabolic Syndrome X/*complications
Obesity/*complications
Overweight
Prevalence
Questionnaires
Risk Factors

Reference

1. Ford ES, Giles WH. A comparison of the prevalence of the metabolic syndrome using two proposed definitions. Diabetes Care. 2003. 26:575–581.

2. Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, Salonen JT. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA. 2002. 288:2709–2716.

3. Jiang X, Srinivasan SR, Webber LS, Wattigney WA, Berenson GS. Association of fasting insulin level with serum lipid and lipoprotein levels in children, adolescents and young adults: the Bogalusa Heart Study. Arch Int Med. 1995. 155:190–196.

4. Ronnemaa T, Knip M, Lautala P, Viikari J, Uhari M, Leino A, Kaprio EA, Salo MK, Dahl M, Nuutinen EM. Serum insulin and other cardiovascular risk indicators in children, adolescents and young adults. Ann Med. 1991. 23:67–72.

5. Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. Prevalence of a metabolic syndrome phenotype in adolescents: findings from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch Pediatr Adolesc Med. 2003. 157:821–827.

6. Sakamoto N, Wansorn S, Tontisirin K, Marui E. A social epidemiologic study of obesity among preschool children in Thailand. Int J Obes Relat Metab Disord. 2001. 25:389–394.

7. Rho JH, Lee DW, Choi JM. Prevalence of childhood obesity in Korea. J Korean Pediatr Soc. 2001. 44:208.

8. Goran MI, Gower BA. Abdominal obesity and cardiovascular risk in children. Coron Artery Dis. 1998. 9:483–487.

9. Arslanian S. Type 2 diabetes in children: clinical aspects and risk factors. Horm Res. 2002. 57:Suppl 1. 19–28.

10. Berenson GS, Srinivasan SR, Bao W, Newman WP III, Rracy RE, Wattigney WA. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. N Engl J Med. 1998. 338:1650–1656.

11. Steinberger J, Daniels SR. Obesity, insulin resistance, diabetes, and cardiovascular risk in children: an American Heart Association scientific statement from the Atherosclerosis, Hypertension, and Obesity in the Young Committee (Council on Cardiovascular Disease in the Young) and the Diabetes Committee (Council on Nutrition, Physical Activity, and Metabolism). Circulation. 2003. 107:1448–1453.

12. Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW, Allen K, Lopes M, Savoye M, Morrison J, Sherwin RS, Caprio S. Obesity and the metabolic syndrome in children and adolescents. N Engl J Med. 2004. 350:2362–2374.

13. de Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ, Newburger JW, Rifai N. Prevalence of the metabolic syndrome in american adolescents: findings from the third National Health and Nutrition Examination Survey. Circulation. 2004. 110:2494–2497.

14. Korean Association of Pediatrics. Hong CE, editor. 1998 KAP growth charts: Korea. Pediatrics. 2002. Seoul: Daehan;1245.

15. Barlow SE, Dietz WH. Obesity evaluation and treatment: Expert Committee recommendations: the Maternal and Child Health Bureau, Health Resources and Services Administration and the Department of Health and Human Services. Pediatrics. 1998. 102:E29.

16. Daniels SR, Khoury PR, Morrison JA. Utility of different measures of body fat distribution in children and adolescents. Am J Epidemiol. 2000. 152:1179–1184.

17. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents. Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents: a working group report from the National High Blood Pressure Education Program. Pediatrics. 1996. 98:649–658.

18. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2004. 27:Suppl 1. S5–S10.

19. Katzmarzyk PT, Pérusse L, Malina RM, Bergeron J, Després JP, Bouchard Cl. Stability of indicators of the metabolic syndrome from childhood and adolescence to young adulthood: the Quebec Family Study. J Clin Epidemiol. 2001. 54:190–195.

20. Chu NF, Rimm EB, Wang DJ, Liou HS, Shieh SM. Relationship between anthropometric variables and lipid levels among school children: the Taipei Children Heart Study. Int J Obes Relat Metab Disord. 1998. 22:66–72.

21. Pereira MA, Jacobs DR Jr, Van Horn L, Slattery ML, Kaartashov AI, Ludwig DS. Diary consumption, obesity and the insulin resistance syndrome in young adults: the CARDIA Study. JAMA. 2002. 287:2081–2089.

22. Reaven GM. Insulin resistance and compensatory hyperinsulinemia: role in hypertension, dyslipidemia, and coronary heart disease. Am Heart J. 1991. 121(pt 2):1283–1288.

23. Liese AD, Mayer-Davis EJ, Tyroler HA, Davis CE, Keil U, Duncan BB, Heiss G. Development of the multiple metabolic syndrome in the ARIC cohort: joint contribution of insulin, BMI, and WHR: Atherosclerosis Risk in Communities. Ann Epidemiol. 1997. 7:407–416.

24. Vanhala MJ, Vanhala PT, Keinanen-Kiukaanniemi SM, Kumpusalo EA, Takala JK. Relative weight gain and obesity as a child predict metabolic syndrome as an adult. Int J Obes Relat Metab Disord. 1999. 23:656–659.

25. Torok K, Szelenyi Z, Porszasz J, Molnar D. Low physical performance in obese adolescent boys with metabolic syndrome. Int J Obes Relat Metab Disord. 2001. 25:966–970.

26. Dietz WH. Health consequences of obesity in youth: childhood predictors of adult disease. Pediatrics. 1998. 101:518–525.