Korean J Intern Med.
2007 Dec;22(4):283-286. 10.3904/kjim.2007.22.4.283.
A Case of Combined Hepatocellular-Cholangiocarcinoma with Underlying Schistosomiasis
- Affiliations
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- 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. jmyangdr@catholic.ac.kr
- 2Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.
- KMID: 1776682
- DOI: http://doi.org/10.3904/kjim.2007.22.4.283
Abstract
- Combined hepatocellular-cholangiocarcinoma is a rare form of primary liver cancer showing features of both hepatocellular and biliary epithelial differentiation. We report here on a case with collision tumor, which apparently was the coincidental occurrence of both hepatocellular carcinoma and cholangiocarcinoma underlying schistosomiasis. A 39-year-old-Philippine female was transferred to our hospital for evaluation of a liver mass that was found on ultrasonography at a local hospital. HBsAg and Anti-HCV were negative and serum alpha-fetoprotein (AFP) level was normal. The tumor mass was histologically diagnosed as adenocarcinoma by sono-guided biopsy before the operation. Partial lobectomy was performed and we histologically identified the concurrent occurrence of hepatocellular carcinoma and cholangiocarcinoma, (a "collision type carcinoma").
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