J Korean Neurol Assoc.
2015 Feb;33(1):36-39.
Neurosyphilis Presenting with Multiple Cranial Neuropathy
- Affiliations
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- 1Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. jkkang@amc.seoul.kr
- 2Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
- 3Division of Infectious Diseases, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Abstract
- Neurosyphilis can present with various clinical symptoms. We report a patient with multiple cranial neuropathy that, mimicked tuberculosis, but was finally diagnosed as neurosyphilis. A 38-year-old man was admitted due to subacutely progressive hearing loss. Brain MRI revealed multiple dural enhanced masses on contrast-enhanced T1 weighted images. Brain biopsy of the dural enhanced lesion revealed chronic granulomatous inflammation with coagulation necrosis, compatible with syphilitic gumma. Serum venereal disease research laboratory and fluorescent treponemal antibody absorption test results were positive. Treatment with penicillin resolved the patient's symptom.
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