Korean J Fertil Steril.
2005 Dec;32(4):325-330.
The Histologic Features of the Uterus and Adnexa Extirpated from Gender Identity Disorder Patients with Depot Androgen Injection
- Affiliations
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- 1Department of Obstetrics and Gynecology, College of Medicine, Dong-A University, Busan, Korea. chamchi@naver.com
- 2Department of Pathology, College of Medicine, Dong-A University, Busan, Korea.
- 3Department of Plastic Surgery, College of Medicine, Dong-A University, Busan, Korea.
Abstract
OBJECTIVE
To investigate the histologic features of the uterus and adnexae extirpated from gender identity disorder (GID) patients that received depot androgen injection.
METHODS
We reviewed the histologic findings of the uterus and adnexae removed from sixteen GID patients, who had taken depot androgen injection for 5~168 months.
RESULTS
Fourteen patients (87.5%) showed the atrophied epithelium of exocervix and all of 16 patients (100%) showed the atrophy of endometrium. Seven patients (43.7%) showed multiple cystic follicles in the ovarian cortex and 6 patients (37.5%), 3 patients (18.7%) showed corpus albicans and corpus luteum, respectively.
CONCLUSIONS
Exogenous androgen induced atrophy of cervix and endometrium. This effect was more prominent in the endometrium. In addition, PCO-like histologic features were observed in the ovary.
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