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Birth of a healthy infant after bone marrow-derived cell therapy

Patel NH, Jadeja YD, Patel NH, Patel MN, Bhadarka HK, Chudasama PN, Thakkar HR

Bone marrow-derived cell (BMDC) therapy has numerous applications as potential biological cells for use in regenerative medicine. Here, we present an original case of endometrial atrophy associated with genital tuberculosis...
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Small testes: clinical characteristics and ultrasonographic findings

Yang DM, Choi HI, Kim HC, Kim SW, Moon SK, Lim JW

The purpose of this pictorial essay is to describe the ultrasonographic and clinical findings of patients with small testes due to a wide range of causes. We retrospectively reviewed the...
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Evaluation of Age- and Radical-Prostatectomy Related Changes in Male Pelvic Floor Anatomy Based on Magnetic Resonance Imaging and 3-Dimensional Reconstruction

Tai JW, Sorkhi SR, Trivedi I, Sakamoto K, Albo M, Bhargava V, Rajasekaran MR

Purpose: Puborectalis muscles (PRM) and ischiocavernosus muscles (ICM) play important roles in urinary continence and male erectile functions. Understanding of anatomy and surgical-injury related changes to these muscles is critical...
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Association between Medial Temporal Atrophy, White Matter Hyperintensities, Neurocognitive Functions and Activities of Daily Living in Patients with Alzheimer’s Disease and Mild Cognitive Impairment

An Mh, Kim H, Lee KJ

Objectives:The aim of this study was to compare activities of daily living (ADLs) according to degenerative changes in brain [i.e., medial temporal lobe atrophy (MTA), white matter hyperintensities] and to...
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Cushing Syndrome Associated Myopathy: It Is Time for a Change

Reincke M

Cushing syndrome is the result of excessive levels of glucocorticoids. Endogenous Cushing syndrome is rare with an incidence of two to three cases per million per year. Clinically, the presentation...
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Decreased Basal Ganglia Volume in Cerebral Amyloid Angiopathy

Fotiadis P, Pasi M, Charidimou A, Warren AD, Schwab KM, Alzheimer’s Disease Neuroimaging Initiative, Rosand J, Grond Jvd, Buchem MAv, Viswanathan A, Gurol ME, Greenberg SM

Background and Purpose Cerebral amyloid angiopathy (CAA) is a common pathology of the leptomeningeal and cortical small vessels associated with hemorrhagic and non-hemorrhagic brain injury. Given previous evidence for CAA-related...
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Clinical Scales Used in Motor Neuron Disease

Oh Si, Park JS, Sung JJ, Kim SH

Motor neuron diseases (MND) are heterogeneous spectra of disorders that that primarily affect the motor neurons (MN) resulting in motor nerve and muscle degeneration. The pathophysiological mechanisms of MN cell...
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Clinical Efficacy of Hormonal and Nonhormonal Agents in the Treatment of Vulvovaginal Atrophy

Ilhan G, Aslan MM, Cevrioglu AS, Yıldırım M, Erkorkmaz U

Objectives: Symptomatic local treatment of vaginal atrophy (VA) in menopausal women includes hormonal and nonhormonal preparations. Some women may be reluctant to use vaginal estradiol preparations because of the concern...
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Prosthetic rehabilitation of an oligodontia patient with atrophic maxilla

Chi SS, Kim YJ, Kang HG, Ko KH, Huh YH, Park CJ, Cho LR

Congenital tooth agenesis is the most common developmental dental anomaly, of which oligodontia is defined as the absence of six or more permanent teeth, except the third molars. Tooth agenesis...
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Tail suspension is useful as a sarcopenia model in rats

Nemoto A, Goyagi T

Background Sarcopenia promotes skeletal muscle atrophy and exhibits a high mortality rate. Its elucidation is of the highest clinical importance, but an animal experimental model remains controversial. In this study, we...
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Structural Changes in the Hippocampal Subfields in Early-Onset Mild Cognitive Impairment

Moon SW, Yoo DY

  • KMID: 2513157
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Feb;27(1):67-73.
Objectives:The aim of this study was to examine the structural change in the hippocampal subfields in early-onset (EO) mild cognitive impairment (MCI) patients associated with the APOE ε4 carrier state. Methods:This...
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Prevalence and pathologic study of porcine epidemic diarrhea in Jeju

Kim HJ, Yang HS, Kang SC, Kim JH

From April 2014 to September 2015, 153 piglets from 52 farms in Jeju were diagnosed with porcine epidemic diarrhea (PED). The major PED cases were focused on suckling piglets (144...
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Correlation between Topographic Progression of Geographic Atrophy and Visual Acuity Changes

You JI, Kim DG, Yu SY, Kim ES, Kim K

Purpose: To analyze topographic progression of geographic atrophy with different concentric circles centered on the fovea in correlation with decrease of visual acuity. Methods: We retrospectively analyzed 36 eyes of 26...
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Effects of exercise on AKT/PGC1-α/FOXO3a pathway and muscle atrophy in cisplatin-administered rat skeletal muscle

Bae JH, Seo DY, Lee SH, Shin C, Jamrasi P, Han J, Song W

Cisplatin has been reported to cause side effects such as muscle wasting in humans and rodents. The physiological mechanisms involved in preventing muscle wasting, such as the regulation of AKT,...
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Factors associated with paravertebral muscle cross-sectional area in patients with chronic low back pain

Cankurtaran D, Yigman ZA, Umay E

Background: This study was performed to reveal the relationships between the cross-sectional areas (CSAs) of the paraspinal muscles and the severity of low back pain (LBP), including the level of...
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Self-care Experiences of Adolescents with Spinal Muscular Atrophy

Yang BH, Chung CY, Weng WC, Lo KW, Li YS

Purpose We examined the self-care experiences of adolescents with spinal muscle atrophy (SMA) and their perceptions of the interactions between their body and the environment. Methods We interviewed ten adolescents with SMA aged...
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Detection of Spinal Muscular Atrophy Using a Duplexed Real-Time PCR Approach With Locked Nucleic Acid-Modified Primers

Pan J, Zhang C, Teng Y, Zeng S, Chen S, Liang D, Li Z, Wu L

Background: Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder mainly caused by homozygous deletions that include exon 7 of the survival motor neuron 1 (SMN1) gene. A nearby...
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Alpha-Synuclein Inclusion Formation in Human Oligodendrocytes

Yoon YS, Ahn WJ, Ricarte D, Ortiz D, Shin CY, Lee SJ, Lee HJ

Multiple system atrophy (MSA) is a neurodegenerative disease characterized by presence of α-synuclein-positive inclusions in the cytoplasm of oligodendrocytes. These glial cytoplasmic inclusions (GCIs) are considered an integral part of...
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Endoscopic Prediction for Acid Reflux in Patients without Hiatus Hernia

Kim JY, Shin IS, Min YW, Kim K, Lee H, Min BH, Lee JH, Kim JJ, Rhee PL

Background/Aims: A diagnosis of gastroesophageal reflux disease is challenging in patients who have reflux symptoms but do not respond to proton pump inhibitors nor have reflux esophagitis and hiatal hernia...
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Bilateral Ocular Toxoplasmosis that Caused Optic Atrophy Secondary to Papillitis

Lee D, Kim M, Moon JW

Purpose: We report a case of ocular toxoplasmosis that caused bilateral optic atrophy secondary to papillitis. Case summary: A 52-year-old male with no history of systemic disease was referred to our...
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