Korean J Urol.  1986 Oct;27(5):773-777.

A Case of Teratoma with Seminoma which Has Elevated Serum Alpha-FP and Beta-HCG

Affiliations
  • 1Department of Urology, College of Medicine, Korea University, College of medicine, Seoul, Korea.

Abstract

Alpha-FP is a major serum binding protein produced by the fetal yolk sac, liver, and gastrointestinal tract. It may be produced by pure embryonal carcinoma, teratocarcinoma, yolk sac tumor, or combined tumors but not by pure choriocarcinoma or pure seminoma. HCG is secreted by the placenta but in germ cell tumors, syncytiotrophoblastic cells have been found responsible for the production of HCG. Recently, we experienced a case of mixed germ cell tumor composed of mainly teratoma and seminoma which is producing alpha-FP and beta-HCG.

Keyword

seminoma; alpha-fetoprotein

MeSH Terms

alpha-Fetoproteins
Carcinoma, Embryonal
Carrier Proteins
Choriocarcinoma
Endodermal Sinus Tumor
Female
Gastrointestinal Tract
Liver
Neoplasms, Germ Cell and Embryonal
Placenta
Pregnancy
Seminoma*
Teratocarcinoma
Teratoma*
Trophoblasts
Yolk Sac
Carrier Proteins
alpha-Fetoproteins
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