Korean J Pediatr.  2005 Jun;48(6):675-677.

Prevention and Dissociation of the Platelet Aggregation in a Patient with EDTA-dependent Pseudothrombocytopenia by Supplementation of Kanamycin: A Case Report

Affiliations
  • 1Department of Pediatrics, Gachon Medical School, Incheon, Korea. isjeon@ghil.com

Abstract

Pseudothrombocytopenia is usually associated with anticoagulant ethylene diaminetetraacetic acid (EDTA). The platelet clumping that occurs in EDTA-dependent pseudothrombocytopenia (EDPT) can sometimes be prevented by the use of other anticoagulants such as heparin or sodium citrate. As an alternative, we used kanamycin before or after the withdrawal of EDTA-anticoagulated blood in a 6-year-old boy with EDPT. Kanamycin used supplementarily during the differentiation of EDPT effectively prevented platelet clumping.

Keyword

Pseudothrombocytopenia; EDTA; Kanamycin

MeSH Terms

Anticoagulants
Blood Platelets*
Child
Citric Acid
Edetic Acid
Heparin
Humans
Kanamycin*
Male
Platelet Aggregation*
Sodium
Anticoagulants
Citric Acid
Edetic Acid
Heparin
Kanamycin
Sodium
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