Korean J Intern Med.
2002 Mar;17(1):69-72.
A Case of NK/T-Cell Lymphoma Complicated by a Squamous Cell Carcinoma of Hard Palate during Combination Chemotherapy and Radiation Therapy
- Affiliations
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- 1Department of Internal Medicine Hanyang University College of Medicine, Seoul, Korea.
- 2Department of Hanyang University Pathology College of Medicine, Seoul, Korea.
Abstract
- NK/T-cell lymphoma, which often shows an angiocentric growth pattern, is a distinct clinicopathologic entity highly associated with Epstein-Barr virus. The disease is characterized by a destruction of the upper respiratory tract, particularly the nasal cavity, palate and paranasal sinuses. Interestingly, NK/T-cell lymphoma is closely linked to a variety of complications, such as hemophagocytic syndrome, second primary cancer, sepsis and bleeding. Here we report a case of a 50-year-old man diagnosed initially as NK/T-cell lymphoma of the oropharynx and who developed a second primary carcinoma of the hard palate during combination chemotherapy and radiation therapy.