Yonsei Med J.  2000 Apr;41(2):293-297. 10.3349/ymj.2000.41.2.293.

Lobular carcinoma in situ in sclerosing adenosis

Affiliations
  • 1Department of Pathology, Yonsei University College of Medicine, Seoul, Korea. jungwh96@yumc.yonsei.ac.kr
  • 2Department of General Surgery, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

The initial presentation of breast malignancy as noninvasive carcinoma in an area of sclerosing adenosis is unusual. Especially, lobular carcinoma in situ in sclerosing adenosis sometimes can be a potential source of confusion with invasive lobular carcinoma. We report a case of lobular carcinoma in situ presenting in adenosis exhibiting patterns akin to invasive lobular carcinoma, thus leading to potential misdiagnosis. Overall architecture of the lesion as seen at lower power and immunohistochemistry can be useful to distinguish between sclerosing adenosis with lobular carcinoma in situ and infiltrating lobular carcinoma.

Keyword

Lobular carcinoma in situ; sclerosing adenosis; immunohistochemistry

MeSH Terms

Breast Neoplasms/pathology*
Carcinoma in Situ/pathology*
Carcinoma, Lobular/pathology*
Case Report
Female
Fibrocystic Disease of Breast/pathology*
Human
Immunohistochemistry
Middle Age
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