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A Comparative Systematic Analysis of The Influence of Microplastics on Colon Cells, Mouse and Colon Organoids

Park SB, Jung WH, Choi KJ, Koh B, Kim KY

BACKGROUND: Microplastics (MPs) are small fragments from any type of plastic formed from various sources, including plastic waste and microfibers from clothing. MPs degrades slowly, resulting in a high probability...
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Congenital Microgastria without Concomitant Anomalies in Adult

An H, Cho YS, Jung WH, Cho HJ, Nam KI

Congenital microgastria is an extremely rare anomaly of which only 60 cases have been described in the literature. Congenital microgastria has been known as a result of impairment of normal...
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Influence of Postconceptional Age on the Renal Biomarkers in Very-Low-Birth-Weight Infants

Lee RS, Shin SY, Jung WH, Park JH

Purpose: We investigated whether consecutive levels of new emerging renal biomarkers, including serum cystatin C (CysC) and urinary neutrophil gelatinase-associated lipocalin (NGAL)/creatinine (Cr) ratio, were affected by postconceptional age in...
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pH-Dependent Expression, Stability, and Activity of Malassezia restricta MrLip5 Lipase

Park M, Lee JS, Jung WH, Lee YW

Background The lipophilic yeasts Malassezia spp. are normally resident on the surface of the human body, and often associated with various skin diseases. Of the 18 known Malassezia spp., Malassezia restricta...
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Silicone Tube Intubation with Lacrimal Endoscopy and Endonasal Dacryocystorhinostomy in Adult Nasolacrimal Duct Obstruction

Jung WH, Lee JH, Kim YJ, Yang JW

Purpose: To compare the success rate of silicone tube intubation using a lacrimal endoscope with that of endonasal dacryocystorhinostomy in adult acquired nasolacrimal duct obstruction with no canalicular obstruction. Methods: Retrospective...
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Retinal Capillary Network in Fellow Eyes with Unilateral Vein Occlusion Using Optical Coherence Tomography Angiography

Jung WH, Kim JL

Purpose: To compare the thickness of the ganglion cell-inner plexiform layer (GCIPL) and the perifoveolar retinal capillary network between fellow eyes with unilateral branch retinal vein occlusion (BRVO) and healthy...
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Macular Pigment Optical Density in the Korean Population: a Cross Sectional Study

Hong IH, Jung WH, Lee JH, Chang IB

BACKGROUND: To evaluate the macular pigment optical density (MPOD) with age in the Korean population using the Macular Pigment Screener II (MPSII®). METHODS: One hundred and twenty-six eyes were retrospectively reviewed....
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Antifungal Mechanism of Action of Lauryl Betaine Against Skin-Associated Fungus Malassezia restricta

Do E, Lee HG, Park M, Cho YJ, Kim DH, Park SH, Eun D, Park T, An S, Jung WH

Betaine derivatives are considered major ingredients of shampoos and are commonly used as antistatic and viscosity-increasing agents. Several studies have also suggested that betaine derivatives can be used as antimicrobial...
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Effects of Intranasal Oxytocin on Emotion Recognition in Korean Male: A Dose-Response Study

Shin NY, Park HY, Jung WH, Kwon JS

OBJECTIVE: Research has shown that intranasal oxytocin affects social cognition and behavior; however, its effects vary based on social context, individual characteristics and dose. The present study aimed to determine...
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Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans

Son YE, Jung WH, Oh SH, Kwak JH, Cardenas M, Park HS

Mon1 is a guanine nucleotide exchange factor subunit that activates the Ypt7 Rab GTPase and is essential for vacuole trafficking and autophagy in eukaryotic organisms. Here, we identified and characterized...
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Azole Resistance Caused by Increased Drug Efflux in Candida glabrata Isolated from the Urinary Tract of a Dog with Diabetes Mellitus

Kim M, Lee H, Hwang SY, Lee I, Jung WH

A yeast-like organism was isolated from a urine sample of a 6-year-old neutered male miniature poodle dog with urinary tract infection, diabetes ketoacidosis, and acute pancreatitis. We identified the yeast-like...
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In Vitro Anti-Malassezia Activity of Castanea crenata Shell and Oil-Soluble Glycyrrhiza Extracts

Han SH, Hur MS, Kim MJ, Jung WH, Park M, Kim JH, Shin HJ, Choe YB, Ahn KJ, Lee YW

BACKGROUND: A new shampoo with anti-Malassezia properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options. OBJECTIVE: The aim of this study...
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Executive Dysfunction in Obsessive-Compulsive Disorder and Anterior Cingulate-Based Resting State Functional Connectivity

Yun JY, Jang JH, Jung WH, Shin NY, Kim SN, Hwang JY, Kwon JS

OBJECTIVE: Executive dysfunction might be an important determinant for response to pharmacotherapy in obsessive-compulsive disorder (OCD), and could be sustained independently of symptom relief. The anterior cingulate cortex (ACC) has...
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Diagnostic Efficacy of the Modified Alvarado Score for Acute Appendicitis in Pregnant Women

Kim CS, Park HI, Lee JH, Jung WH, Lee SH, Nho WY, Kim SH, Je DW, Choe MS, Lee JY, Bae JK, Je SM, Chung TN, Kim EC, Choi SW, Kim OJ

PURPOSE: We aimed to evaluate whether the modified Alvarado score-which is currently being used to diagnose acute appendicitis-can be applicable in the diagnosis of diseases in pregnant women. METHODS: We retrospectively...
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Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study

Youn HJ, Kim SY, Park M, Jung WH, Lee YW, Choe YB, Ahn KJ

BACKGROUND: Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis. OBJECTIVE: We aimed to determine whether a cream containing climbazole/piroctone olamine (C/P cream), antifungal...
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Huge Benign Prostatic Hyperplasia

Byun HJ, Shin TJ, Jung WH, Ha JY, Park CH, Kim CI

Benign prostatic hyperplasia (BPH) is one of the most common diseases in older men and it may be accompanied with significant problems in the quality of life. Histological changes of...
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Lymphangiogenesis in Breast Cancer Correlates with Matrix Stiffness on Shear-Wave Elastography

Cha YJ, Youk JH, Kim BG, Jung WH, Cho NH

PURPOSE: To correlate tumor stiffness and lymphangiogenesis in breast cancer and to find its clinical implications. MATERIALS AND METHODS: A total of 140 breast cancer patients were evaluated. Tumor stiffness was...
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Pathologic Evaluation of Breast Cancer after Neoadjuvant Therapy

Park CK, Jung WH, Koo JS

Breast cancer, one of the most common cancers in women, has various treatment modalities. Neoadjuvant therapy (NAT) has been used in many clinical trials because it is easy to evaluate...
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Interobserver Variability of Ki-67 Measurement in Breast Cancer

Chung YR, Jang MH, Park SY, Gong G, Jung WH, The Korean Breast Pathology Ki-67 Study Group

BACKGROUND: As measurement of Ki-67 proliferation index is an important part of breast cancer diagnostics, we conducted a multicenter study to examine the degree of concordance in Ki-67 counting and...
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Current Issues and Clinical Evidence in Tumor-Infiltrating Lymphocytes in Breast Cancer

Ahn SG, Jeong J, Hong S, Jung WH

With the advance in personalized therapeutic strategies in patients with breast cancer, there is an increasing need for biomarker-guided therapy. Although the immunogenicity of breast cancer has not been strongly...
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