Korean J Radiol.  2007 Oct;8(5):452-455. 10.3348/kjr.2007.8.5.452.

Myxoid Chondrosarcoma of the Sinonasal Cavity in a Child: a Case Report

• Kim YJ
• Im SA
• Lim GY
• Chun HJ
• Park HJ
• Kim MS
• Choi YJ

• KMID: 1734296
• DOI: http://doi.org/10.3348/kjr.2007.8.5.452

Abstract

Chondrosarcomas are malignant tumors of cartilage that rarely involve the sinonasal region, and myxoid chondrosarcoma is a rare histologic variant of chondrosarcoma that usually occurs in the soft tissue of extremities. Although several case reports and results of small series of chondrosarcomas in the sinonasal region in children are available, myxoid type chondrosarcoma is extremely rare. We recently experienced a case of low grade myxoid chondrosarcoma involving the sinonasal cavity in a 10-year-old boy, and here we report its radiologic-pathologic findings. In this case, chondroid calcification on CT and septal and marginal enhancement on MRI suggested a chondrosarcoma. Whole body PET-CT demonstrated no definite metastatic lesion and a low peak standardized uptake value primary tumor. However, no definite distinguishing imaging features were observed that distinguished low grade myxoid chondrosarcoma from conventional chondrosarcoma.

Keyword

Myxoid chondrosarcoma; Sinonasal cavity; Child; Computed tomography (CT); Magnetic resonance (MR); PET-CT

MeSH Terms

Bone Neoplasms/*diagnosis/radiotherapy/surgery
Child
Chondrosarcoma/*diagnosis/radiotherapy/surgery
Diagnosis, Differential
Follow-Up Studies
Humans
Magnetic Resonance Imaging
Male
Myxosarcoma/*diagnosis/radiotherapy/surgery
Nasal Cavity/*pathology/*radiography/surgery
Paranasal Sinuses/*pathology/*radiography/surgery
Positron-Emission Tomography
Rare Diseases
Tomography, X-Ray Computed
Whole Body Imaging

Figure

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  Fig. 1 Non-enhanced axial CT scan showing a lobulated hypoattenuating mass in the right nasal cavity and nasal septum, containing ring and arc calcifications (arrows). The bony margins of the medial orbital wall were thin and expanded, without definite evidence of bony destruction.

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  Fig. 2 A, B. Coronal and axial T2 weighted MR images (TR/TE, 4530/110) showing a high signal intensity mass located in the right posterior nasal cavity and on the nasal septum, and extending into the right ethmoid sinus. Areas of low signal intensity (arrows) on T2-weighted images corresponded to matrix mineralization on CT images. The mass displaced and compressed the right medial orbital wall laterally and the cribriform plate superiorly. C. Axial T1 weighted image (TR/TE, 921/11) showing the homogeneously hypointense mass. D. Contrast-enhanced T1-weighted image showing peripheral and septal-like enhancement with a focal area of strong enhancement (asterisk) at the anterior portion of the mass.

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  Fig. 3 PET-CT image showing mild F18-fluorodeoxyglucose (FDG) uptake (pSUV = 2.7) (arrows) in the right nasal cavity and on the nasal septum.

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  Fig. 4 Photomicrograph of the resected tumor (Hematoxylin & Eosin, ×400). A cord-like cellular arrangement of pleomorphic chondroblasts (arrows) with thin anastomosing strands is shown surrounded by myxoid stroma (asterisks).

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