Yonsei Med J.  1982 Jun;23(1):75-79. 10.3349/ymj.1982.23.1.75.

The Experimental Study of Corneocytes after Acute Skin Irritation (I)

• Lee S
• Park YK
• Kim YK

• KMID: 1729494
• DOI: http://doi.org/10.3349/ymj.1982.23.1.75

Abstract

This study was designed to investigate the effects on count, size, and morphology of human corneocytes when the skin is irritated with a rough towel. The desquamating portion of the stratum corneum was sampled with the detergent scrub technique every other day for 12 days. The following parameters were measured; numerical count, size (surface (mu)2), and shape (regular, irregular). Corneocytes from skin irritated with a rough towel differed from those of normal skin in that they were diminished by about 60% in count and were 14% smaller in size on the first experimental day. These parameters became normalized in count after 10 days and in size after 5 days respectively. On the morphological classification of the cell outlines, there were no significant differences from the control groupts except that there were slightly increased numbers of irregular cells in the experimental groups.

Keyword

Corneocytes; acute irritation

MeSH Terms

Adult
Baths*
Bedding and Linens*
Epidermis/cytology*
Human
Male