Yonsei Med J.  2011 Jul;52(4):630-634. 10.3349/ymj.2011.52.4.630.

Clinical Review of Endogenous Endophthalmitis in Korea: A 14-Year Review of Culture Positive Cases of Two Large Hospitals

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 3Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea. cokim@yuhs.ac
  • 4Center for Infectious Diseases, National Medical Center, Seoul, Korea.

Abstract

PURPOSE
To identify the clinical features and outcomes of endogenous endophthalmitis in Korea.
MATERIALS AND METHODS
We reviewed 18 patients with endogenous endophthalmitis at 2 Korean hospitals, treated over a 14 year period between January 1993 and December 2006.
RESULTS
The comorbidities observed in these cases were diabetes mellitus and liver cirrhosis. The most common pathogens, which were found in 7 patients each (38.9%), were Klebsiella pneumonia and Pseudomonas aeruginosa. All patients were treated with systemic antibiotics and fortified topical antibiotics. A surgical approach including vitrectomy was performed in 9 cases (50.0%). The prognosis was generally poor, and visual acuity improved slightly in 6 patients (33.3%).
CONCLUSION
In this study, diabetes mellitus and Klebsiella pneumonia showed a close relationship with endogenous endophthalmitis, respectively. Endogenous endophthalmitis is a serious risk to sight and careful attention to establishing the diagnosis and management may decrease the ocular morbidity.

Keyword

Endophthalmitis; Klebsiella pneumonia; Pseudomonas aeruginosa; liver abscess; diabetes mellitus

MeSH Terms

Aged
Diabetes Complications/*epidemiology/microbiology
Endophthalmitis/complications/*epidemiology/microbiology
Female
Humans
Incidence
Klebsiella pneumoniae/isolation & purification
Liver Cirrhosis/*complications/epidemiology/microbiology
Male
Middle Aged
Pseudomonas aeruginosa/isolation & purification
Republic of Korea/epidemiology
Retrospective Studies

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