Yonsei Med J.  2011 Jul;52(4):630-634. 10.3349/ymj.2011.52.4.630.

Clinical Review of Endogenous Endophthalmitis in Korea: A 14-Year Review of Culture Positive Cases of Two Large Hospitals

• Chung KS
• Kim YK
• Song YG
• Kim CO
• Han SH
• Chin BS
• Gu NS
• Jeong SJ
• Baek JH
• Choi JY
• Kim HY
• Kim JM

• KMID: 1727996
• DOI: http://doi.org/10.3349/ymj.2011.52.4.630

Abstract

PURPOSE
To identify the clinical features and outcomes of endogenous endophthalmitis in Korea.
MATERIALS AND METHODS
We reviewed 18 patients with endogenous endophthalmitis at 2 Korean hospitals, treated over a 14 year period between January 1993 and December 2006.
RESULTS
The comorbidities observed in these cases were diabetes mellitus and liver cirrhosis. The most common pathogens, which were found in 7 patients each (38.9%), were Klebsiella pneumonia and Pseudomonas aeruginosa. All patients were treated with systemic antibiotics and fortified topical antibiotics. A surgical approach including vitrectomy was performed in 9 cases (50.0%). The prognosis was generally poor, and visual acuity improved slightly in 6 patients (33.3%).
CONCLUSION
In this study, diabetes mellitus and Klebsiella pneumonia showed a close relationship with endogenous endophthalmitis, respectively. Endogenous endophthalmitis is a serious risk to sight and careful attention to establishing the diagnosis and management may decrease the ocular morbidity.

Keyword

Endophthalmitis; Klebsiella pneumonia; Pseudomonas aeruginosa; liver abscess; diabetes mellitus

MeSH Terms

Aged
Diabetes Complications/*epidemiology/microbiology
Endophthalmitis/complications/*epidemiology/microbiology
Female
Humans
Incidence
Klebsiella pneumoniae/isolation & purification
Liver Cirrhosis/*complications/epidemiology/microbiology
Male
Middle Aged
Pseudomonas aeruginosa/isolation & purification
Republic of Korea/epidemiology
Retrospective Studies

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