Korean J Pathol.
2000 Jul;34(7):534-536.
Adenoid Basal Cell Tumor of the Prostate: A case report
- Affiliations
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- 1Department of Pathology, Eulji University School of Medicine.
- 2Department of Pathology, Chonbuk National University Medical School, Institute of Medical Science, Chonju 561-180, Korea.
- 3Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine.
Abstract
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Adenoid basal cell tumor of the prostate is a rare tumorous lesion that can be misdiagnosed
as adenocarcinoma of the prostate. The malignant potential of adenoid basal cell tumor remains
uncertain due to small number of reported cases. This 66-year-old man presented with symptoms
of urinary tract obstruction. Under the impression of benign prostatic hyperplasia, a transurethral
resection of the prostate (TURP) was performed. The patient was alive with no evidence of
recurrence or metastasis 15 months after TURP. Microscopically, most of the lesions were
composed of nodular collections of small nests of basaloid cells with peripheral palisading, and
clusters of tumor cells forming cribriform pattern. Multiple areas of basal cell hyperplasia and
atypical basal cell hyperpalsia were also observed. The coexistence of basal cell hyperplasia,
atypical basal cell hyperpalsia, and adenoid basal cell tumor with cribriform pattern in this case
supports a morphologic continuum from the benign hyperplastic lesion to malignant neoplasia.