Korean J Pathol.  1991 Jun;25(3):245-249.

Two Cases of Black Adenoma of the Adrenal Cortex Associated with Cushing's Syndrome

Affiliations
  • 1Department of Pathology, School of Medicine, Kyung Hee University, Seoul, Korea.

Abstract

Black adenoma is known to be a rare variant of adrenal cortical adenoma containing characteristic abundant lipofuscin pigments in the cytoplasm. Almost all of them are nonfunctioning and only occasionally they are associated with Cushing's syndrome or primary hyperaldosteronism. We present two cases of black cortical adenoma of the adrenal gland associated with Cushing's syndrome in a 24-year-old woman and a 64-year-old man. This report dealt with clinical and pathologic presentation including ultrastructural identification of lipofuscin pigment.

Keyword

Black adenoma; Lipofuscin pigment; Cushing's syndrome; Adrenal gland

MeSH Terms

Female
Male
Humans
Adenoma
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