Korean J Med.  2005 Aug;69(2):216-221.

A case of pseudo-Cushing's syndrome with unilateral nonfunctioning adrenal adenoma

Affiliations
  • 1Department of Internal Medicine, Konkuk University College of Medicine, Seoul, Korea. mijin71@naver.com
  • 2Department of Radiology, Konkuk University College of Medicine, Seoul, Korea.

Abstract

A pseudo-Cushing's state can be defined as some or all of the clinical features of Cushing's syndrome together with some evidence for hypercortisolism. It may be related to depression, alcohol abuse and obesity. Its manifestation may be transient and resolved with abstinence from causing factors. We report a case of a 70-year-old woman with unilateral nonfunctioning adrenal adenoma and geriatric depressive disorder, which diagnosed by Geriatric Depression Scale (GDS). She showed clinical and/or biochemical features of Cushing's syndrome. Low dose and high dose dexamethasone suppression tests were not identical to those in ACTH independent Cushing's syndrome. Few cases of pseudo-Cushing's syndrome were reported previously in Korea but there was no report about pseudo-Cushing's syndrome combined with nonfunctional adrenal adenoma.

Keyword

Cushing's syndrome; Depression; Adrenal gland; Adenoma

MeSH Terms

Adenoma*
Adrenal Glands
Adrenocorticotropic Hormone
Aged
Alcoholism
Cushing Syndrome
Depression
Depressive Disorder
Dexamethasone
Female
Humans
Korea
Obesity
Adrenocorticotropic Hormone
Dexamethasone
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