Korean J Med.  2013 Sep;85(3):324-328. 10.3904/kjm.2013.85.3.324.

Solitary Splenic Metastasis from Head and Neck Cancer: A Case Report

Affiliations
  • 1Department of Internal Medicine, Seoul National University Hospital, Seoul National University Collge of Medicine, Seoul, Korea. bhumsuk@snu.ac.kr
  • 2Department of Otorhinolaryngology, Seoul National University Hospital, Seoul National University Collge of Medicine, Seoul, Korea.
  • 3Department of Radiation Oncology, Seoul National University Hospital, Seoul National University Collge of Medicine, Seoul, Korea.

Abstract

Solitary splenic metastases from head and neck cancer are rare. We report a 35-year-old male with nasal cavity cancer with metastasis to the cervical lymph nodes. The patient underwent three cycles of induction chemotherapy, followed by left medial maxillectomy with modified radical neck dissection and concurrent chemoradiotherapy with weekly cisplatin. After 7 months of a disease-free interval, positron-emission tomography showed a high uptake in the spleen, and a biopsy confirmed metastatic carcinoma. After four cycles of systemic chemotherapy with docetaxel and cisplatin, laparoscopic splenectomy was performed. This case highlights that solitary splenic metastasis, although rare, may occur with a locoregionally controlled head and neck cancer and could be treated with local and systemic treatment.

Keyword

Solitary splenic metastasis; Head and neck cancer; Splenectomy

MeSH Terms

Adult
Biopsy
Chemoradiotherapy
Cisplatin
Head
Head and Neck Neoplasms
Humans
Induction Chemotherapy
Lymph Nodes
Male
Nasal Cavity
Neck
Neck Dissection
Neoplasm Metastasis
Positron-Emission Tomography
Spleen
Splenectomy
Taxoids
Cisplatin
Taxoids
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