Korean J Pathol.
2008 Oct;42(5):317-322.
Solitary Splenic Metastases from Uterine Cervical Cancer: Case Reports and Review of the Literature
- Affiliations
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- 1Department of Pathology, Chonnam National University Medical School, Gwangju, Korea. cchoi@chonnam.ac.kr
- 2Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.
- 3Brain Korea 21 Project for Biomedical Human Resources Center at Chonnam National University, Gwangju, Korea.
Abstract
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Splenic metastasis from gynecologic tumors is extremely rare, especially in the absence of apparent disease at other sites. We report two patients that underwent splenectomy for a solitary splenic metastasis from uterine cervical carcinoma. In case 1, a 54-year-old woman with FIGO Stage IIb squamous cell carcinoma of the uterine cervix treated with radiotherapy and chemotherapy developed a solitary splenic metastasis 10 months after initial treatment. In case 2, a 46-year-old woman with FIGO Stage IIb adenocarcinoma of the uterine cervix treated with radiotherapy and chemotherapy was found to have a solitary splenic metastasis 11 months after treatment. Thus all abdominal organs including the spleen must be evaluated for metastases during follow-up of gynecologic tumors.