J Korean Assoc Maxillofac Plast Reconstr Surg.  2011 Sep;33(5):420-424.

Guided Bone Regeneration Using a Putty-type Demineralized Bone Matrix: Case Report

• Jang HS
• Kim SG
• Moon SY
• Oh JS
• Park JJ
• Jeong MA
• Yang SJ
• Jung JW
• Kim JS

Abstract

Allomatrix (Wright Medical Tech, Inc., Arlington, Tenn, USA), is a newly designed, injectable putty with a reliable demineralized bone matrix (DBM), derived from human bone. The compound contains 86% DBM and other bone growth factors such as bone morphogenic protein (BMP)-2, BMP-4, insulin-like growth factor (IGF)-1, and transforming growth factor (TGF)-beta1. It has excellent osteoinduction abilities. In addition, DBM is known to have osteoconduction capacity as a scaffold due to its collagen matrix. This product contains a powder, which is a mix of DBM and surgical grade calcium sulfate as a carrier. A practitioner can blend the powder with calcium sulfate solution, making a putty-type material which has the advantages of ease of handling, better fixation, and no need for a membrane, because it can function as membrane itself. This study reports the clinical and radiographic results of various guided bone regeneration cases using Allomatrix, demonstrating its strong potential as a graft material.

Keyword

Bone morphogenic protein; Demineralized bone matrix; Growth factor; Osteoinduction

MeSH Terms

Bone Development
Bone Matrix
Bone Regeneration
Calcium Sulfate
Collagen
Handling (Psychology)
Humans
Membranes
Transforming Growth Factors
Transplants
Calcium Sulfate
Collagen
Transforming Growth Factors