J Adv Prosthodont.  2013 May;5(2):167-171. 10.4047/jap.2013.5.2.167.

Guided bone regeneration using demineralized allogenic bone matrix with calcium sulfate: case series

• Kim YK
• Lee JY
• Kim SG
• Lim SC

• KMID: 2284757
• DOI: http://doi.org/10.4047/jap.2013.5.2.167

Abstract

PURPOSE
The purpose of this case series was to evaluate the effect of guided bone regeneration using demineralized allogenic bone matrix with calcium sulfate.
MATERIALS AND METHODS
Guided bone regeneration using Demineralized Allogenic Bone Matrix with Calcium Sulfate (AlloMatrix(TM), Wright. USA) was performed at the time of implant placement from February 2010 to April 2010. At the time of the second surgery, clinical evaluation of bone healing and histologic evaluation were performed. The study included 10 patients, and 23 implants were placed. The extent of bony defects around implants was determined by measuring the horizontal and vertical bone defects using a periodontal probe from the mesial, distal, buccal, and lingual sides and calculating the mean and standard deviation of these measurements. Wedge-shaped tissue samples were obtained from 3 patients and histologic examination was performed.
RESULTS
In clinical evaluation, it was observed that horizontal bone defects were completely healed with new bones, and in the vertical bone defect area, 15.1% of the original defect area remained. In 3 patients, histological tests were performed, and 16.7-41.7% new bone formation was confirmed. Bone graft materials slowly underwent resorption over time.
CONCLUSION
AlloMatrix(TM) is an allograft material that can be readily manipulated. It does not require the use of barrier membranes, and good bone regeneration can be achieved with time.

Keyword

Calcium sulfate; Demineralized bone matrix

MeSH Terms

Bone Matrix
Bone Regeneration
Calcium
Calcium Sulfate
Humans
Membranes
Osteogenesis
Transplantation, Homologous
Transplants
Calcium
Calcium Sulfate

Figure

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  Fig. 1 Revitalization of the implant chips (white asterisks) with some degree of woven formation around the implant chips. Absorbing implant chips (black asterisks) were found in the fibrous tissue.

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  Fig. 2 Active woven bone forming anastomosing bony trabeculae around the implant chips (arrows) was identified.

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  Fig. 3 Active new bone formation around the implant chips (white asterisks). Some implant chips (black asterisks) were found in the fibrous tissue devoid of new bone formation.

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