Korean J Parasitol.  2003 Mar;41(1):57-61. 10.3347/kjp.2003.41.1.57.

A survey on head lice infestation in Korea (2001) and the therapeutic efficacy of oral trimethoprim/sulfamethoxazole adding to lindane shampoo

Affiliations
  • 1Department of Parasitology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea. tsyong212@yumc.yonsei.ac.kr
  • 2Department of Parasitology, Yonsei University Wonju College of Medicine, Wonju 220-701, Korea.
  • 3Department of Clinical Pathology, Shinheung College, Uijeongbu 480-701, Korea.

Abstract

Total of 7, 495 children including 3, 908 boys and 3, 587 girls from a kindergarten and 15 primary schools were examined for head lice infestation (HLI). The overall prevalence of HLI in this study was found to be 5.8%. Head lice were much more commonly detected in girls than in boys with prevalence of 11.2% and 0.9%, respectively. Sixty-nine children with HLI were treated with 1% lindane shampoo alone (group 1), and 45 children with HLI were treated with 1% lindane shampoo and oral trimethoprim/sulfamethoxazole (group 2), and follow-up visits were conducted 2 and 4 weeks later. The children who still had HLI 2 weeks after the primary treatment were treated again. At the 2-week follow-up visit, the treatment success rates of groups 1 and 2 were 76.8% and 86.7%, respectively, and at the 4-week follow-up visit, the rates were 91.3% and 97.8%, respectively. No statistically significant synergistic effect was observed for the combination of a 1% lindane shampoo and oral trimethoprim/sulfamethoxazole.


MeSH Terms

Animals
Anti-Infective Agents/therapeutic use
Child
Drug Therapy, Combination
Female
*Hair Preparations
Health Surveys
Humans
Korea/epidemiology
Lice Infestations/*drug therapy/*epidemiology
Lindane/*therapeutic use
Male
*Pediculus
Prevalence
Students
Trimethoprim-Sulfamethoxazole Combination/*therapeutic use
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