Korean J Parasitol.  2013 Jun;51(3):305-311. 10.3347/kjp.2013.51.3.305.

Hyperendemicity of Haplorchis taichui Infection among Riparian People in Saravane and Champasak Province, Lao PDR

Affiliations
  • 1Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
  • 2Department of Environmental Medical Biology and Institute of Tropical Medicine and Arthropods of Medical Resource Bank, Yonsei University College of Medicine, Seoul 120-752, Korea. tsyong212@gmail.com
  • 3Department of Parasitology, School of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea.
  • 4Department of Microbiology and Immunology, School of Medicine, Eulji University, Daejeon 301-746, Korea.
  • 5Department of Hygiene and Prevention, Ministry of Public Health, Vientiane, Lao PDR.
  • 6Department of Parasitology, College of Medicine, Korea University, Seoul 136-705, Korea.

Abstract

In this study, we found that Haplorchis taichui, a heterophyid intestinal fluke, is highly prevalent, with heavy worm loads, among riparian people in Saravane and Champasak province, Lao PDR. Fecal specimens were collected from 1,460 people (717 men and 743 women) in 12 riparian (Mekong river) districts and were examined by the Kato-Katz fecal smear technique. The overall helminth egg positive rate was 78.8% and 66.4% in Saravane and Champasak province, respectively. The positive rate for small trematode eggs (STE), which included H. taichui and other heterophyids, Opisthorchis viverrini, and lecithodendriids, was 69.9% and 46.3% in Saravane and Champasak province, respectively. To obtain adult flukes, 30 STE-positive people were treated with 40 mg/kg praziquantel and then purged. Whole diarrheic stools were collected 4-5 times for each person and searched for fluke specimens using a stereomicroscope. Mixed infections with various species of trematodes (H. taichui, Haplorchis pumilio, O. viverrini, Prosthodendrium molenkampi, Centrocestus formosanus, and Echinochasmus japonicus) and a species of cestode (Taenia saginata) were found. However, the worm load was exceptionally high for H. taichui compared with other trematode species, with an average of 21,565 and 12,079 specimens per infected person in Saravane and Champasak province, respectively, followed by H. pumilio (41.9 and 22.5, respectively) and O. viverrini (9.4 and 1.5, respectively). These results show that diverse species of intestinal and liver flukes are prevalent among riparian people in Saravane and Champasak province, Lao PDR, with H. taichui being the exceptionally dominant species.

Keyword

Haplorchis taichui; Haplorchis pumilio; Opisthorchis viverrini; Centrocestus formosanus; hyperinfection; prevalence; riparian people; Saravane province; Champasak province; Lao PDR

MeSH Terms

Adolescent
Adult
Aged
Aged, 80 and over
Animals
Child
Demography
Endemic Diseases/*statistics & numerical data
Feces/parasitology
Female
Humans
Laos/epidemiology
Male
Middle Aged
Parasite Egg Count
Rivers
*Trematoda
Trematode Infections/*parasitology
Young Adult
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