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Effect of Temperature on the Killing of Opisthorchis viverrini Eggs In Vitro

Boueroy P, Duenngai K, Eamudomkarn C, Sripan P, Boonmars T, Pumhirunroj B, Artchayasawat A, Songsri J, Chomphumee K, Rattanasuwan P, Laummaunwai P, Khueangchiangkhwang S, Boonjaraspinyo S

Contaminated liver fluke egg in the environment has led to the high prevalence of human opisthorchiasis associated with cholangiocarcinoma in Southeast Asia. To find the effective lessening methods of Opisthorchis...
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Comparative Characterization of Four Calcium-Binding EF Hand Proteins from Opisthorchis viverrini

Emmanoch P, Kosa N, Vichasri-Grams S, Tesana S, Grams R, Geadkaew-Krenc A

Four isoforms of calcium binding proteins containing 2 EF hand motifs and a dynein light chain-like domain in the human liver fluke Opisthorchis viverrini, namely OvCaBP1, 2, 3, and 4,...
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Echinostoma ilocanum Infection in Two Residents of Savannakhet Province, Lao PDR

Chai JY, Sohn WM, Cho J, Eom KS, Yong TS, Min DY, Hoang EH, Phommasack B, Insisiengmay B, Rim HJ

Adult specimens of Echinostoma ilocanum (Garrison, 1908) Odhner, 1911 (Trematoda: Echinostomatidae) were recovered from 2 riparian people who resided along the Mekong River in Savannakhet Province, Lao PDR. In fecal...
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Molecular and Biochemical Characterization of Opisthorchis viverrini Calreticulin

Chaibangyang W, Geadkaew-Krenc A, Vichasri-Grams S, Tesana S, Grams R

Calreticulin (CALR), a multifunctional protein thoroughly researched in mammals, comprises N-, P-, and C-domain and has roles in calcium homeostasis, chaperoning, clearance of apoptotic cells, cell adhesion, and also angiogenesis....
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Subsets of Inflammatory Cytokine Gene Polymorphisms are Associated with Risk of Carcinogenic Liver Fluke Opisthorchis viverrini-Associated Advanced Periductal Fibrosis and Cholangiocarcinoma

Surapaitoon A, Suttiprapa S, Mairiang E, Khuntikeo , Pairojkul , Bethony J, Brindley P, Sripa B

Opisthorchis viverrini infection induces chronic inflammation, and a minor proportion of infected individuals develop advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA). Inflammatory cytokines and/or their gene polymorphisms may link to...
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Prevalence of Opisthorchis viverrini-Like Fluke Infection in Ducks in Binh Dinh Province, Central Vietnam

Dao TT, Abatih EN, Nguyen TT, Tran HT, Gabriël S, Smit S, Le PN, Dorny P

Following the first report of Opisthorchis viverrini infection in a domestic duck in Phu My District of Binh Dinh Province, Central Vietnam, many other cases were observed in the province....
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Infection Status of Zoonotic Trematode Metacercariae in Fishes from Vientiane Municipality and Champasak Province in Lao PDR

Eom KS, Park HS, Lee D, Sohn WM, Yong TS, Chai JY, Min DY, Rim HJ, Insisiengmay B, Phommasack B

The infection status of fishborne zoonotic trematode (FZT) metacercariae was investigated in fishes from 2 localities of Lao PDR. Total 157 freshwater fishes (17 species) were collected in local markets...
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Chronic Opisthorchis viverrini Infection and Associated Hepatobiliary Disease Is Associated with Iron Loaded M2-like Macrophages

Bility MT, Sripa B

Chronic Opisthorchis viverrini-induced hepatobiliary disease is associated with significant leukocyte infiltration, including activated macrophages; however, the polarization of infiltrating macrophages remains to be fully characterized. In this study, we characterized...
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Prevalence of Helminthic Infections among Inhabitants of Lao PDR

Eom KS, Yong TS, Sohn WM, Chai JY, Min DY, Rim HJ, Jeon HK, Banouvong , Insisiengmay B, Phommasack B

The prevalence of helminthic infections was surveyed on a total of 6,178 residents (males 2,549 and females 3,629) in 102 villages of 9 provinces in Lao PDR between 2007 and...
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Zoonotic Trematode Metacercariae in Fish from Phnom Penh and Pursat, Cambodia

Chai JY, Sohn WM, Na BK, Yong TS, Eom KS, Yoon CH, Hoang EH, Jeoung HG, Socheat D

A survey was performed to investigate the infection status of freshwater fish with zoonotic trematode metacercariae in Phnom Penh and Pursat Province, Cambodia. All collected fish with ice were transferred...
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A Cross-Sectional Study on Intestinal Parasitic Infections in Rural Communities, Northeast Thailand

Boonjaraspinyo S, Boonmars T, Kaewsamut , Ekobol N, Laummaunwai P, Aukkanimart R, Wonkchalee N, Juasook A, Sriraj P

Despite the existence of effective anthelmintics, parasitic infections remain a major public health problem in Southeast Asia, including Thailand. In rural communities, continuing infection is often reinforced by dietary habits...
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Establishment of an Allo-Transplantable Hamster Cholangiocarcinoma Cell Line and Its Application for In Vivo Screening of Anti-Cancer Drugs

Puthdee N, Vaeteewoottacharn K, Seubwai W, Wonkchalee O, Kaewkong W, Juasook A, Pinlaor S, Pairojkul , Wongkham C, Okada S, Boonmars T, Wongkham S

Opisthorchis viverrini (O. viverrini) is a well-known causative agent of cholangiocarcinoma (CCA) in humans. CCA is very resistant to chemotherapy and is frequently fatal. To understand the pathogenesis of CCA...
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Distribution and Abundance of Opisthorchis viverrini Metacercariae in Cyprinid Fish in Northeastern Thailand

Pinlaor S, Onsurathum S, Boonmars T, Pinlaor P, Hongsrichan N, Chaidee A, Haonon O, Limviroj W, Tesana S, Kaewkes S, Sithithaworn P

To increase public health awareness for prevention of opisthorchiasis caused by eating raw freshwater fish, the distribution and abundance of Opisthorchis viverrini metacercariae (OV MC) was investigated in freshwater fish...
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Curcumin Prevents Bile Canalicular Alterations in the Liver of Hamsters Infected with Opisthorchis viverrini

Jattujan P, Pinlaor S, Charoensuk L, Arunyanart C, Welbat JU, Chaijaroonkhanarak W

Opisthorchis viverrini infection causes inflammation and liver injury leading to periductal fibrosis. Little is known about the pathological alterations in bile canaliculi in opisthorchiasis. This study aimed to investigate bile...
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Molecular Differentiation of Opisthorchis viverrini and Clonorchis sinensis Eggs by Multiplex Real-Time PCR with High Resolution Melting Analysis

Kaewkong W, Intapan PM, Sanpool O, Janwan P, Thanchomnang T, Laummaunwai P, Lulitanond V, Doanh PN, Maleewong

Opisthorchis viverrini and Clonorchis sinensis are parasites known to be carcinogenic and causative agents of cholangiocarcinoma in Asia. The standard method for diagnosis for those parasite infections is stool examination...
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Histopathological Changes in Tissues of Bithynia siamensis goniomphalos Incubated in Crude Extracts of Camellia Seed and Mangosteen Pericarp

Aukkanimart R, Boonmars T, Pinlaor S, Tesana S, Aunpromma , Booyarat C, Sriraj P, Laummaunwai P, Punjaruk W

  • KMID: 1792145
  • Korean J Parasitol.
  • 2013 Oct;51(5):537-544.
The present study was performed to observe histopathological changes in tissues of Bithynia siamensis goniomphalos (Gastropoda, Bithyniidae) incubated in crude extract solutions of camellia (Camellia oleifera) seed and mangosteen (Garcinia...
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Hyperendemicity of Haplorchis taichui Infection among Riparian People in Saravane and Champasak Province, Lao PDR

Chai JY, Yong TS, Eom KS, Min DY, Jeon HK, Kim TY, Jung BK, Sisabath L, Insisiengmay B, Phommasack B, Rim HJ

In this study, we found that Haplorchis taichui, a heterophyid intestinal fluke, is highly prevalent, with heavy worm loads, among riparian people in Saravane and Champasak province, Lao PDR. Fecal...
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Fishborne Trematode Metacercariae in Luang Prabang, Khammouane, and Saravane Province, Lao PDR

Rim HJ, Sohn WM, Yong TS, Eom KS, Chai JY, Min DY, Lee SH, Hoang EH, Phommasack B, Insisiengmay S

Fishborne trematode (FBT) metacercariae were investigated in fish from 3 Provinces of Lao PDR. Total 242 freshwater fish of 40 species were collected in local markets of Luang Prabang (59...
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High Prevalence of Opisthorchis viverrini Infection in a Riparian Population in Takeo Province, Cambodia

Yong TS, Shin EH, Chai JY, Sohn WM, Eom KS, Lee DM, Park K, Jeoung HG, Hoang EH, Lee YH, Woo HJ, Lee JH, Kang SI, Cha JK, Lee KH, Yoon CH, Sinuon M, Socheat D

Opisthorchis viverrini infection was found to be highly prevalent in 3 riverside villages (Ang Svay Chek A, B, and C) of the Prey Kabas District, Takeo Province. This area is...
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High Prevalence of Haplorchis taichui, Phaneropsolus molenkampi, and Other Helminth Infections among People in Khammouane Province, Lao PDR

Chai JY, Han ET, Shin EH, Sohn WM, Yong TS, Eom KS, Min DY, Um JY, Park MS, Hoang EH, Phommasack B, Insisiengmay B, Lee SH, Rim HJ

The prevalence of liver and intestinal helminth infections, including Opisthorchis, Haplorchis, Phaneropsolus, hookworms, Enterobius, and Taenia, was surveyed in Khammouane province, Lao PDR. Fecal specimens were collected from 1,242 people...
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