Korean J Parasitol.  1995 Dec;33(4):395-398. 10.3347/kjp.1995.33.4.395.

A human case of invasive fascioliasis associated with liver abscess

• Kim JB
• Kim DJ
• Huh S
• Cho SY

• KMID: 1715385
• DOI: http://doi.org/10.3347/kjp.1995.33.4.395

Abstract

A 56 year-old Korean housewife/farmer/goat keeper suffered from right upper quadrant pain and fever with chills. In the abdominal sonogram and computerized tomography, multiple, 2-3 cm, irregular shaped cavities were observed in the right lobe of liver. A liver biopsy revealed extensive central necrosis with Characot-Leyden crystals surrounded by palisading histiocytes, eosinophil-rich inflammatory infiltration. Worm was not observed. However, the serologic test for Fasciola-specific IgG antibody by micro-ELISA was positive. Prior antibody levels did not differ and eosinophilia persisted 6 and 16 months after praziquantel treatment although the cavitary lesions in the liver disappeared 6 months after the treatment. Reported herein is a human case of invasive fascioliasis diagnosed clinically by a combination of radiological, histopathological and serological studies.

MeSH Terms

Animal
Antibodies, Helminth/ANALYSIS
Antiplatyhelmintic Agents/THERAPEUTIC USE
Case Report
Enzyme-Linked Immunosorbent Assay
Fascioliasis/DRUG THERAPY/*DIAGNOSIS
Female
Human
IgG/ANALYSIS
Liver Abscess/*COMPLICATIONS
Middle Age
Praziquantel/THERAPEUTIC USE
Serodiagnosis