Clin Mol Hepatol.  2013 Sep;19(3):309-314. 10.3350/cmh.2013.19.3.309.

Genotype-4 hepatitis E in a human after ingesting roe deer meat in South Korea

Affiliations
  • 1Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea. lyreju@naver.com
  • 2Division of Enteric and Hepatitis Viruses, Korea Centers for Disease Control and Prevention, Korea National Institute of Health, Osong, Korea.

Abstract

The recent increase in the number of cases of indigenous hepatitis E virus (HEV) infection highlights the importance of identifying the transmission routes for the prevention of such infections. Presented herein is the first case of acute HEV infection after ingesting wild roe deer meat in South Korea. A 43-year-old male presented with abdominal discomfort and jaundice. He had not recently traveled abroad, but had eaten raw roe-deer meat 6-8 weeks before the presentation. On the 7th day of hospitalization the patient was diagnosed with acute viral hepatitis E. Phylogenetic analysis of his serum revealed genotype-4 HEV. This case supports the possibility of zoonotic transmission of HEV because the patient appears to have been infected with genotype-4 HEV after ingesting raw deer meat.

Keyword

Genotype 4 hepatitis E; Roe deer; South Korea

MeSH Terms

Adult
Alanine Transaminase/blood
Animals
Bilirubin/blood
Deer/virology
Genotype
Hepatitis E/*diagnosis/transmission/virology
Hepatitis E virus/classification/*genetics/isolation & purification
Humans
Male
Phylogeny
RNA, Viral/analysis
Republic of Korea
Travel
Alanine Transaminase
Bilirubin
RNA, Viral
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