Obstet Gynecol Sci.  2014 May;57(3):236-239. 10.5468/ogs.2014.57.3.236.

A case of huge retroperitoneal liposarcoma in pregnancy

• Oh SE
• Kim HJ
• Choi SJ
• Oh SY
• Roh CR
• Kim JH

• KMID: 1704432
• DOI: http://doi.org/10.5468/ogs.2014.57.3.236

Abstract

A 39-year-old woman was referred to our hospital at 28+2 week gestation. Routine obstetric examination revealed a palpable pelvic mass. Initial investigation by magnetic resonance imaging demonstrated a huge solid mass with heterogeneous enhancement that completely filled the right side of the abdomen. She underwent two surgeries: a programmed cesarean section by Department of Obstetrics and Gynecology team and a laparotomy performed by the General Surgery team. Final diagnosis was de-differentiated liposarcoma (French Federation Nationale des Centres de Lutte Contre le Cancer grade 2/3). She has been treated with radiation therapy focusing on high risk area of retroperitoneum followed by adjuvant chemotherapy (doxorubicin and ifosfamide). Below is the full case with literature review.

Keyword

Adjuvant; Chemoradiotherapy; Operation; Pregnancy; Retroperitoneal liposarcoma

MeSH Terms

Abdomen
Adult
Cesarean Section
Chemoradiotherapy
Chemotherapy, Adjuvant
Diagnosis
Female
Gynecology
Humans
Laparotomy
Liposarcoma*
Magnetic Resonance Imaging
Obstetrics
Pregnancy*

Figure

• 

  Fig. 1 Abdominopelvic computed tomography images after cesarean section. There is about 27 cm sized probable liposarcoma originating from peritoneal space containing fat tissues in them. (A) Sagittal view and (B) coronal view.

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  Fig. 2 Macroscopic findings. Dedifferentiated liposarcoma in retroperitoneum. The cut section of the retroperitoneal mass shows a heterogenous multiloculated mass with large portion of hemorrhage and some necrotic portion (about 60%).

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