J Korean Soc Magn Reson Med.  2014 Mar;18(1):64-69. 10.13104/jksmrm.2014.18.1.64.

Pancreatic Adenosquamous Cell Carcinoma with Solitary Liver Metastasis Showing Different Imaging Features

  • 1Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Gyeonggi-do, Korea. sahcha@kumc.or.kr


Among exocrine pancreatic tumors, adenosquamous carcinoma is a rare, aggressive subtype with a poor prognosis and a high potential for metastases compared with its more conventional glandular counterpart, adenocarcinoma of the pancreas. We herein describe the imaging findings of pancreatic adenosquamous cell carcinoma with solitary liver metastasis showing different imaging features and also review the previous literature to recognize characteristic imaging features of pancreatic adenosquamous cell carcinoma.


Pancreas; Adenosquamous; Carcinoma; Magnetic resonance imaging (MRI)

MeSH Terms

Carcinoma, Adenosquamous
Neoplasm Metastasis*


  • Fig. 1 a. In the pancreas head and uncinate process, a relatively ill-defined, low-attenuation mass invading the duodenal wall shows poor enhancement on contrast enhanced image. There is no evidence of tumor necrosis. b. A solitary, hypodense, metastatic nodule in segment 5 of the liver is noted on an enhanced CT scan. c. On a contrast-enhanced T1-weighted image of arterial (20s) phase, mass in the pancreas shows heterogeneous enhancement. d. A solitary hepatic metastatic nodule appears as an area of high-signal intensity on a T2-weighted image, suggesting that the tumor has undergone necrotic change. e. The pancreatic mass itself shows heterogeneous slight high SI on T2-weighted image. f, g. The pancreas and the liver masses shows high SI on high b value image with diffusion restrictioned. h. Hematoxylin and eosin (H & E) staining of a pancreatic adenosquamous carcinoma with a glandular component shows ductal and glandular structures (× 400). i. H & E staining of a pancreatic adenosquamous carcinoma with a squamous component shows an intercellular bridge (× 400).


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