Korean J Dermatol.  1989 Feb;27(1):89-93.

A Case of Paraneoplastic Acrokeratosis (Bazex' Syndrome)

• Kim ST
• Suh KS
• Park MK
• Chae YS

Abstract

We report a case of paraneoplastic acrokeratosis(Bazex syndrome) occurring in a 70 year old man with small cell carcinoma of the lung. The skin lesions showed violaceous erythema and psoriasiform scaling of the face, aural helices, scalp, and palmoplantar regions with severe nail dystrophy, Histcipathological findings revealed hyperkeratosis, acanthosis and spongiosis in the epiderrnis, and lyrnphocytic infiltration in the upper dermis. He was treated with cis-diamine dichloroplanum(Cisplan), 4 o-demethy-l-o-epipodo- phyllotoxin (Etoposide ) and steroid onitrnent. But eight months later, he died of lung carcinoma.

Keyword

Paraneoplastic acrokeratosis; Small cell carcinoma of the lung

MeSH Terms

Aged
Carcinoma, Small Cell
Dermis
Erythema
Humans
Lung
Scalp
Skin