J Korean Ophthalmol Soc.
1967 Dec;8(3):37-41.
Osteogenic Sarcoma following Irradiation for Retinoblastoma
- Affiliations
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- 1Department of Ophthalmology, School of Medicine, Seoul National Univertity, Seoul, Korea.
- 2Department of Ophthalmology, Seoul Red Cross Hospital, Seoul, Korea.
- 3Department of Pathology, School of Medicine, Seoul National University, Seoul, Korea.
Abstract
- A case of Osteogenic sarcoma arised from orbit 4 years after the radiation therapy for retinoblastoma in a 9 years old girl is presented. 4 Years ago, under the diagnosis of retinoblastoma, the left orbital exenteration was performed and was treated with x-ray radiation giving 4.500 gamma tumor dose in 4, weeks. On admission, the left orbital cavity was filled with hard mass and orbital bone revealed extensive destruction with osteoplastic changes on x-ray, and diffuse sarcomatous growth of anaplastic cells with abundant osteogenesis and osteoclastic activity microscopically. It is of authors' opinion that osteogenic sarcoma of orbital bone in this presented case might developed by irradition on retinoblastoma.
