Korean J Dermatol.  1974 Jun;12(2):9-15.

Twenty Six Cases of Exfoliative Dermatitis: It's Clinical, Etiological, Laboratory Findings and Courses of Treatment, with Review of Literatures

• Ihm CW
• Kim YP

Abstract

Twenty six cases of Exfoliative dermatitis were found during the years from July of 1967 to June of 1972 at the department of dermatology of Chonnarn University Hospital, and the cases of the disease were studied for ciinical signs and symptoms, etiological factors, laboratory findings and responses to the treatment. The incidence of the disease to total number of skin patients in the years: 0. 2%, mean age distribution: 41. 9 years old, and the most cornmon etiological factors: drugs such as 4. 4-diaminodiphenylsulfone (dapsone, DDS), mercurial preparations, herbs and arsenicals in order, were found. The distinct laboratory findings of the disease revealed leukocytosis, eosinophilia and hypoproteinemia. However, the results of liver function tests (SGOT, SGPT, CCF, TTT, Alk. phosphatase) were found to be generally within normal limits in cases of hypoproteinernia. The clinical symptoms of the disease appeared to be lymphadenopathy, coated or avitaminosis type glossitis or stomtitis with characteristic skin lesions of the disease. In the treatment of the disease, the authors emphasized careful treatment to correct fluid and electrolyte balance and hypoproteinemia with adequate topical skin management. The authors also had discussions of the etiological factors comparing with other literatures, clinical signs and symptoms, therapeutical achievement and problems, and reviewed the literatures of the disease.

MeSH Terms

Age Distribution
Alanine Transaminase
Arsenicals
Avitaminosis
Child
Dermatitis, Exfoliative*
Dermatology
Eosinophilia
Glossitis
Humans
Hypoproteinemia
Incidence
Leukocytosis
Liver Function Tests
Lymphatic Diseases
Skin
Water-Electrolyte Balance
Alanine Transaminase
Arsenicals