J Korean Neurol Assoc.
1986 Dec;4(2):239-245.
Chronic Polyneuropathy with Monoclonal Gammopathy of Undetermined Significance
- Affiliations
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- 1Department of Neurology, College of Medicine, Seoul National University.
- 2Department of Pathology, College of Medicine, Seoul National University.
Abstract
- Diseases of the peripheral nervous system are one of the most difficult subjects in neurology partly in that specific etiologies are often not found. Among peripheral neuropathies of unknown causes, an association of monoclonal gammopathies has been observed. Monoclonal gammopathies are disorders characterized by proliferation of a single clone of plasma cell that produces monoclonal proteins. Here we report two cases of chronic sensorimotor polyneuropathy with monoclonal gummopathy of undetermined significance, who showed no evidences of multiple myeloma, macroglobulinemia, systemic amyloidosis, or other neoplasms. One case is also associated with hyperthyroidism and cryoglobulinemia.
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