Korean J Med.  2004 Apr;66(4):449-452.

A case of primary undifferentiated cardiac sarcoma originated from left atrium

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Inha University, Inchon, Korea. moonhlmd@inha.ac.kr
  • 2Department of Pathology, College of Medicine, Inha University, Inchon, Korea.
  • 3Department of Thoracic and Cardiovascular Surgery, College of Medicine, Inha University, Inchon, Korea.

Abstract

Primary undifferentiated cardiac sarcomas are extremely rare, and typically undergo aggressive local spread. The prognosis of undifferentiated sarcoma is reported to be very poor even if surgical resection, with or without adjuvant chemotherapy and radiotherapy, is performed. Here we present our case of primary undifferentiated sarcoma of the left atrium. A 33-year-old woman presented with a month history of progressive breathlessness and exertional chest pain. Transthoracic echocardiography showed a large mobile mass obstructing much of the left atrium. At surgery a superseptal approach to the atria enabled removal of all the left heart tumor which was attached to the left upper pulmonary vein. Immunochemistry staining revealed the undifferentiated atrial sarcoma. She received three cycles of darcabazine and adriamycin and after three months there was evidence of tumor recurrence. Eleven months later from operation, she died with congestive heart failure.

Keyword

Undifferentiated sarcoma

MeSH Terms

Adult
Chemotherapy, Adjuvant
Chest Pain
Doxorubicin
Echocardiography
Female
Heart Atria*
Heart Failure
Heart Neoplasms
Humans
Immunochemistry
Prognosis
Pulmonary Veins
Radiotherapy
Recurrence
Sarcoma*
Doxorubicin
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