Korean J Hematol.  2002 Aug;37(3):223-226.

A Case of Acute Monoblastic Leukemia with Hexasomy 8

Affiliations
  • 1Department of Clinical Pathology, College of Medicine, Yeungnam University, Daegu, Korea. chscp@hanmail.net
  • 2Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Korea.

Abstract

Additional copies of chromosome 8 are nonrandom karyotypic aberrations in myeloid malignancies with trisomy 8 being the most common. Hexasomy 8 is extremely rare and only two cases have been reported. We report a case of acute myeloid leukemia with hexasomy 8 as a sole karyotypic aberration by conven-tional cytogenetic analysis. The patient was diagnosed as acute monoblastic leukemia and showed short survival.

Keyword

Karyotypic aberration; Hexasomy 8; Acute monoblastic leukemia

MeSH Terms

Chromosomes, Human, Pair 8
Cytogenetic Analysis
Humans
Leukemia, Monocytic, Acute*
Leukemia, Myeloid, Acute
Trisomy
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