J Korean Neurol Assoc.
2006 Dec;24(6):535-543.
Analysis of 10,811 Cases with Acute Ischemic Stroke from Korean Stroke Registry: Hospital-Based Multicenter Prospective Registration Study
- Affiliations
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- 1Department of Neurology, Hallym University College of Medicine, Korea. ssbrain@hallym.ac.kr
- 2Department of Neurology, Eulji University School of Medicine, Korea.
- 3Department of Neurology, University of Ulsan College of Medicine, Korea.
- 4Department of Neurology, Inje University College of Medicine, Korea.
- 5Department of Neurology, Seoul National University Boramae Hospital, Korea.
- 6Department of Neurology, Inha University College of Medicine, Korea.
- 7Department of Neurology, Seoul National University College of Medicine, Korea.
- 8Department of Neurology, Chonnam National University Medical School, Korea.
- 9Department of Neurology, Gachon Medical School, Korea.
- 10Department of Neurology, Kyunghee University College of Medicine, Korea.
- 11Department of Neurology, Pusan National University College of Medicine, Korea.
- 12Department of Neurology, Soonchunhyang University College of Medicine, Korea.
- 13Department of Neurology, Korea University College of Medicine, Korea.
- 14Department of Neurology, Ewha Womans University College of Medicine, Korea.
- 15Department of Neurology, Yonsei University College of Medicine, Korea.
- 16Department of Neurology, Hanyang University College of Medicine, Korea.
- 17Department of Neurology, Sungkyunkwan University School of Medicine, Korea.
- 18Department of Neurology, Dong-A University College of Medicine, Korea.
- 19Department of Neurology, National Health Insurance Corporation Ilsan Hospital, Korea.
- 20Department of Neurology, KwangMyungSungAe Hospital, Korea.
- 21Department of Neurology, Bundang Seoul National University Hospital, Korea.
Abstract
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BACKGROUND: Although several hospital-based stroke studies were published, there has not been any reliable data representing the clinical characteristics of stroke in Korea. We analyzed the clinical characteristics of patients with ischemic stroke registered in the Korean Stroke Registry (KSR), which is the largest prospective hospital-based nation-wide stroke registry in Korea.
METHODS
The KSR provided standardized protocols for collecting data, which includes the data of demographics, subtypes of stroke, risk factors, and neurological outcome at discharge. The brain imaging studies, including CT or MRI, were performed in all cases.
RESULTS
KSR registered 10,811 patients of acute ischemic stroke between Nov. 2002 and Jun. 2004. The large-artery atherosclerosis was the most common subtype (37.3%), followed by small vessel occlusion (30.8%). Hypertension (65.4%) was the most common risk factor, followed by smoking (34.5%) and diabetes (28.3%). Although most of the hypertensive and diabetic patients had been diagnosed before the stroke, less than 45.4% and 32.5% of them were under regular control. The steno-occlusive lesion of extracranial carotid artery was only 29.3% and the ratio of intra- to extracranial artery disease was more than 2 in KSR. Only 20.5% of patients were admitted within 3 hours after stroke onset and 2.1% were treated with intravenous thrombolysis. In-hospital case-fatality was 5.2%, which is relatively comparable to those of previous studies.
CONCLUSIONS
The KSR provided informative data in understanding the clinical characteristics of ischemic stroke in Korea. Further analysis of KSR will facilitate clinical trials and development of guidelines for the management of stroke patients.
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