J Korean Neurol Assoc.  2005 Feb;23(1):117-120.

Imaging Evidence of Basal Ganglia Pathology in Hemi choreoballistic Movement of the Patient with Nonketotic Hyperglycemia: Case Report with Serial Follow Up of Neuroimages

Affiliations
  • 1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. scpark@yumc.yonsei.ac.kr
  • 2Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Korea.

Abstract

The mechanism of chorea underlying nonketotic hyperglycemia was controversial. Serial follow up of brain MRI, 99mTc-ECD SPECT, and 18F-FDG PET in conjunction with clinical observation was done to clarify the pathologic localization. From the functional neuroimages, according to the clinical improvement, the relevant pathology was localized on the lentiform nucleus, mainly on the putamen. In caudate, the mismatch between glucose metabolism and blood flow was observed during and after choreoballistic movement which suggested an important cue to understand the pathogenesis of chorea.

Keyword

Hyperglycemia; Chorea; Putamen

MeSH Terms

Basal Ganglia*
Brain
Chorea
Corpus Striatum
Cues
Fluorodeoxyglucose F18
Follow-Up Studies*
Glucose
Humans
Hyperglycemia*
Magnetic Resonance Imaging
Metabolism
Pathology*
Putamen
Tomography, Emission-Computed, Single-Photon
Fluorodeoxyglucose F18
Glucose
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