Korean J Nephrol.
2002 Mar;21(2):317-321.
A Case of Mesangial IgM Nephropathy without Proteinuria
- Affiliations
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- 1Department of Internal Medicine, Chonbuk National University Medical School, Chonju, Korea. hope@moak.chonbuk.ac.kr
- 2Department of Pathology, Chonbuk National University Medical School, Chonju, Korea.
Abstract
- An 51-year-old woman presented with microscopic hematuria without protenuria for long time. Laboratory studies demonstrated the presence of red blood cells in urine, a normal serum IgM level, the absence of antinuclear antibodies, and a normal complement level. Renal biopsy revealed that some glomeruli are enlarged with endocapillary cell proliferation and a few glomeruli exhibit prominent vascular pole of the tufts and segmental increase in mesangial cell and matrix. Immunofluorescence studies demonstrated segmental granular deposits for IgM. Electron microscopy showed well-preserved foot process associated with focal effacement. Biopsy findings were consistent with IgM nephropathy. We present this case to promote understanding of the pathogenesis of IgM nephropathy.
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